Song Wei, Peng Chuanyi, Liu Yuxin, Han Fang, Zhu Haitao, Zhou Dianbing, Wang Yu, Chen Lijun, Meng Xiaodi, Hou Ruyan
Technical Center for Hefei Customs, Hefei 230022, China.
Anhui Province Key Laboratory of Analysis and Detection for Food Safety, Technical Center for Hefei Customs, Hefei 230022, China.
Toxics. 2023 Jun 16;11(6):537. doi: 10.3390/toxics11060537.
An optimized quick, easy, cheap, effective, rugged, and safe (QuEChERS) technique was investigated and compared with the conventional QuEChERS technique for the simultaneous analysis of fifty-three pesticide residues in safflower using ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS).
Graphitic carbon nitride (g-CN) consisting of a major amount of carbon and nitrogen with a large surface area was used as a QuEChERS adsorbent instead of graphitized carbon black (GCB) for safflower extraction purification. Validation experiments were performed using spiked pesticide samples, and real samples were analyzed.
The linearity of the modified QuEChERS technique was evaluated with high coefficients of determination (R-2) being higher than 0.99. The limits of detection were <10 μg/kg. The spiked recoveries ranged from 70.4% to 97.6% with a relative standard deviation of less than 10.0%. The fifty-three pesticides exhibited negligible matrix effects (<20%). Thiamethoxam, acetamiprid, metolachlor, and difenoconazole were detected in real samples using an established method.
This work provides a new g-CN-based modified QuEChERS technique for multi-pesticide residue analysis in complex food matrices.
研究一种优化的快速、简便、廉价、高效、耐用且安全（QuEChERS）技术，并将其与传统的QuEChERS技术进行比较，以使用超高效液相色谱 - 串联质谱法（UHPLC - MS/MS）同时分析红花中的53种农药残留。
使用由大量碳和氮组成且具有大表面积的石墨相氮化碳（g-CN）作为QuEChERS吸附剂，替代石墨化炭黑（GCB）用于红花提取纯化。使用加标农药样品进行验证实验，并分析实际样品。
改进的QuEChERS技术的线性通过高测定系数（R-2）高于0.99进行评估。检测限<10μg/kg。加标回收率范围为70.4%至97.6%，相对标准偏差小于10.0%。53种农药表现出可忽略不计的基质效应（<20%）。使用既定方法在实际样品中检测到了噻虫嗪、啶虫脒、异丙甲草胺和苯醚甲环唑。
这项工作为复杂食品基质中的多农药残留分析提供了一种基于g-CN的新型改进QuEChERS技术。
Zotero 插件
