Górski A, Mularczyk A
Arch Immunol Ther Exp (Warsz). 1978;26(1-6):975-9.
Neutrophils obtained from peripheral blood of renal allograft recipients were studied for their ability to kill Gram-positive and Gram-negative bacteria as well as to enhance intracellular metabolism measured by the reduction of NBT salts. In addition, the influence of sera these patients on normal cells was investigated. At the same time, these cells were also tested for candidacidal activity. The data derived from these studies indicate that phagocytic cells from these patients are impaired with respect to their capacity to fight the pathogenic microorganisms as well as their sera do not promote normal killing of microorganisms, while the NBT reaction is not changed significantly. Large doses of steroids and rejection crises do not appear to affect dramatically these functions, while an ATG therapy abolishes neutrophil killing ability.
对从肾移植受者外周血中获取的中性粒细胞进行了研究，以考察其杀灭革兰氏阳性菌和革兰氏阴性菌的能力，以及通过NBT盐还原法测定的增强细胞内代谢的能力。此外，还研究了这些患者的血清对正常细胞的影响。同时，还对这些细胞的杀念珠菌活性进行了检测。这些研究得出的数据表明，这些患者的吞噬细胞在对抗病原微生物的能力方面存在缺陷，并且他们的血清也不能促进对微生物的正常杀灭，而NBT反应没有明显变化。大剂量类固醇和排斥反应危机似乎并未显著影响这些功能，而抗胸腺细胞球蛋白疗法则消除了中性粒细胞的杀伤能力。
