Department of Physical Medicine and Rehabilitation, Rutgers New Jersey Medical School, Newark, NJ, USA.
Spinal Cord Ser Cases. 2023 Jun 27;9(1):21. doi: 10.1038/s41394-023-00580-8.
This is a case of acute onset unilateral Bell's Palsy during COVID-19 illness, coinciding with development of progressive leg pain, weakness, and sensation change. The patient was ultimately found to have a large B-cell lymphoma mass invading the sciatic nerve, lumbosacral plexus and the spinal canal with compression of cauda equina consistent with neurolymphomatosis. Although COVID-19 infection has been associated with Bell's palsy, Bell's palsy has also been reported with lymphoid malignancy. We review current literature on the association of Bell's palsy with COVID-19 infection and lymphoid malignancy, as well as review the diagnostic challenges of neurolymphomatosis. Providers should be aware of the possible association of Bell's palsy as harbinger of lymphoid malignancy.
这是一例 COVID-19 期间急性单侧贝尔氏麻痹病例,同时出现进行性腿部疼痛、无力和感觉改变。最终发现患者患有大 B 细胞淋巴瘤肿块,侵犯坐骨神经、腰骶丛和椎管,并伴有马尾神经根受压,符合神经淋巴瘤病。虽然 COVID-19 感染与贝尔氏麻痹有关,但也有报道称贝尔氏麻痹与淋巴恶性肿瘤有关。我们回顾了 COVID-19 感染和淋巴恶性肿瘤与贝尔氏麻痹之间关联的现有文献,并回顾了神经淋巴瘤病的诊断挑战。临床医生应该意识到贝尔氏麻痹可能是淋巴恶性肿瘤的先兆。