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新冠疫情是否真的增加了周围性面瘫的发病率?

Does the SARS-CoV-2 pandemic really increase the frequency of peripheral facial palsy?

机构信息

Istanbul Medeniyet University, Faculty of Medicine, Department of Otorhinolaryngology, Istanbul, Turkey; Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkey.

Istanbul Medeniyet University, Faculty of Medicine, Department of Otorhinolaryngology, Istanbul, Turkey; Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkey.

出版信息

Am J Otolaryngol. 2021 Sep-Oct;42(5):103032. doi: 10.1016/j.amjoto.2021.103032. Epub 2021 Apr 7.

Abstract

PURPOSE

Publications about increased number of peripheral facial paralysis in the COVID-19 pandemic emerged in the literature. However, these studies comprised of an estimate rather than a broad analysis of exact numbers. In this study, we planned to investigate whether the pandemic really resulted in an increase in facial paralysis cases admitted to the hospital by evaluating the cases who applied to our hospital due to facial paralysis in the COVID-19 pandemic year and in the previous 4 years.

MATERIALS AND METHODS

Patients who applied to our hospital due to facial paralysis between March 2016-February 2017 (Group 1), between March 2017-February 2018 (Group 2), between March 2018-February 2019 (Group 3), between March 2019-February 2020 (Group 4), and between March 2020-February 2021 (Group 5) were investigated and detailed data were noted.

RESULTS

156, 164, 149, 172 and 157 patients were admitted to the hospital due to peripheral facial paralysis in Group 1, 2, 3, 4, and 5, respectively. Of these patients, 155, 164, 145, 169, and 153 were Bell's palsy, respectively. SARS-CoV-2 RT-PCR test was positive in only 2 of the 153 patients who were diagnosed in the year of the pandemic.

CONCLUSIONS

This study showed that the number of peripheral facial paralysis detected during the COVID-19 pandemic was similar to previous years. Very few number of positive SARS-CoV-2 RT-PCR test results may have been found incidentally in Bell's palsy patients. Theses stating that SARS-CoV-2 causes peripheral facial paralysis should be supported by laboratory studies and postmortem research.

摘要

目的

文献中出现了 COVID-19 大流行期间周围性面神经麻痹发生率增加的相关报道。然而,这些研究只是对确切数字的估计,而不是广泛的分析。在这项研究中,我们计划通过评估因 COVID-19 大流行期间和之前 4 年期间因面瘫就诊于我院的病例,来调查大流行是否真的导致住院的面瘫病例增加。

材料和方法

我们对 2016 年 3 月至 2017 年 2 月(第 1 组)、2017 年 3 月至 2018 年 2 月(第 2 组)、2018 年 3 月至 2019 年 2 月(第 3 组)、2019 年 3 月至 2020 年 2 月(第 4 组)和 2020 年 3 月至 2021 年 2 月(第 5 组)期间因周围性面瘫就诊于我院的患者进行了调查,并记录了详细数据。

结果

第 1 组、第 2 组、第 3 组、第 4 组和第 5 组分别有 156、164、149、172 和 157 例患者因周围性面瘫住院。这些患者中,155、164、145、169 和 153 例分别为贝尔氏麻痹。在被诊断为大流行年的 153 例患者中,仅 2 例 SARS-CoV-2 RT-PCR 检测结果为阳性。

结论

本研究表明,COVID-19 大流行期间检测到的周围性面瘫病例与前几年相似。在贝尔氏麻痹患者中偶然发现的 SARS-CoV-2 RT-PCR 检测阳性结果非常少。认为 SARS-CoV-2 引起周围性面瘫的说法应得到实验室研究和尸检研究的支持。

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