正压通气顺应性对阻塞性睡眠呼吸暂停患者咽喉反流的影响。
Effect of positive airway pressure compliance on laryngopharyngeal reflux in obstructive sleep apnea patients.
机构信息
Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, 90110, Songkhla, Thailand.
出版信息
BMC Res Notes. 2023 Jun 27;16(1):124. doi: 10.1186/s13104-023-06390-3.
OBJECTIVES
To determine the effect of continuous positive airway pressure (CPAP) compliance on symptoms and signs of laryngopharyngeal reflux (LPR) in patients with obstructive sleep apnea (OSA).
RESULTS
Thirty patients were included. The participants were divided into good compliance (n = 21) and poor compliance (n = 9) groups. After 6-month CPAP treatment, the reflux symptom index score significantly decreased in both the good compliance group (20 (17,24) vs. 14 (10,18), p < 0.001) and the poor compliance group (21 (18,25) vs. 10 (5,16), p < 0.05). Reflux finding score was significantly reduced in both the good compliance group (8 (6,9) vs. 4 (3,5), p < 0.001) and the poor compliance group (6 (4,8) vs. 3 (2,4), p < 0.05). However, there were no statistically significant differences between the groups. CPAP treatment reduces the symptoms and signs of LPR. However, CPAP compliance does not correlate with improvement in LPR in patients with OSA.
目的
确定持续气道正压通气（CPAP）顺应性对阻塞性睡眠呼吸暂停（OSA）患者咽喉反流（LPR）症状和体征的影响。
结果
纳入 30 例患者。将参与者分为顺应性良好组（n=21）和顺应性差组（n=9）。CPAP 治疗 6 个月后，顺应性良好组的反流症状指数评分显著降低（20（17，24）比 14（10，18），p<0.001），顺应性差组也显著降低（21（18，25）比 10（5，16），p<0.05）。顺应性良好组的反流发现评分显著降低（8（6，9）比 4（3，5），p<0.001），顺应性差组也显著降低（6（4，8）比 3（2，4），p<0.05）。然而，两组之间没有统计学上的显著差异。CPAP 治疗可减轻 LPR 的症状和体征。然而，CPAP 顺应性与 OSA 患者 LPR 的改善无关。
Zotero 插件