Sharifkazemi Mohammadbagher, Mohseni-Badalabadi Reza, Kasaie Mohammad, Ahmadi Leila
Cardiology Department, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz 7193613311, Iran.
Tehran Heart Center, Cardiology Department, Tehran University of Medical Sciences, Tehran 5166614711, Iran.
Life (Basel). 2023 May 23;13(6):1231. doi: 10.3390/life13061231.
Non-compaction of the ventricle (NCV) with a higher tendency to left ventricular involvement (NCLV) is a genetic disorder which can cause arrhythmias and cardiac arrest or remain asymptomatic. It is generally considered an isolated disease most frequently, while a few case reports have reported its association with cardiac anomalies. As the treatment strategies differ for NCV and cardiac anomalies, missed diagnosis of the concomitant cardiac diseases can result in poor response to treatment and prognosis. Here, we present 12 adult patients diagnosed with NCV and associated cardiovascular anomalies. By increasing the clinical suspicion and physician's awareness about the possibility of the presence of other cardiovascular diseases with NCLV and using close examination and follow-up of the patients, we could diagnose this number of patients during 14 months of investigation. This case series emphasizes the need for increased awareness and attention of echocardiographers on the diagnosis of other cardiovascular diseases associated with NCV for a better response to treatment and improved patient prognosis.
心室致密化不全（NCV）且左心室受累倾向较高（NCLV）是一种遗传性疾病，可导致心律失常和心脏骤停，或无症状。它通常最常被视为一种孤立性疾病，而少数病例报告称其与心脏异常有关。由于NCV和心脏异常的治疗策略不同，漏诊合并的心脏疾病会导致治疗反应不佳和预后不良。在此，我们报告12例诊断为NCV并伴有心血管异常的成年患者。通过提高临床怀疑度以及医生对NCLV合并其他心血管疾病可能性的认识，并对患者进行密切检查和随访，我们在14个月的调查期间诊断出了这一数量的患者。本病例系列强调，超声心动图检查人员需要提高对与NCV相关的其他心血管疾病诊断的认识并予以关注，以便更好地进行治疗并改善患者预后。
