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Ischemic stroke mortality and time for hospital arrival: analysis of the first 90 days.缺血性脑卒中死亡率与入院时间:90 天内分析。
Rev Esc Enferm USP. 2023 Apr 14;57:e20220309. doi: 10.1590/1980-220X-REEUSP-2022-0309en. eCollection 2023.
2
Is the National Institute of Health Stroke Scale a valid prognosticator of the aftermath in patients with ischemic stroke?国立卫生研究院卒中量表能否有效预测缺血性卒中患者的预后?
J Family Med Prim Care. 2022 Nov;11(11):7185-7190. doi: 10.4103/jfmpc.jfmpc_611_22. Epub 2022 Dec 16.
3
Computed tomography in acute intracerebral hemorrhage: neuroimaging predictors of hematoma expansion and outcome.急性脑出血的计算机断层扫描:血肿扩大及预后的神经影像学预测指标
Insights Imaging. 2022 Nov 22;13(1):180. doi: 10.1186/s13244-022-01309-1.
4
Association of Perfusion Lesion Variables With Functional Outcome in Patients With Mild Stroke and Large Vessel Occlusion Managed Medically.大血管闭塞性轻度卒中经药物治疗患者的灌注损伤变量与功能结局的相关性。
Neurology. 2023 Feb 7;100(6):e627-e638. doi: 10.1212/WNL.0000000000201498. Epub 2022 Oct 28.
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European Stroke Organisation guidelines on treatment of patients with intracranial atherosclerotic disease.欧洲卒中组织关于颅内动脉粥样硬化疾病患者治疗的指南。
Eur Stroke J. 2022 Sep;7(3):III-IV. doi: 10.1177/23969873221099715. Epub 2022 Jun 3.
6
2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.2022年美国心脏协会/美国心脏病学会/美国心力衰竭学会心力衰竭管理指南:执行摘要:美国心脏病学会/美国心脏协会临床实践指南联合委员会报告
J Am Coll Cardiol. 2022 May 3;79(17):1757-1780. doi: 10.1016/j.jacc.2021.12.011. Epub 2022 Apr 1.
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Short-term and Long-term Risk of Stroke in Patients With Perioperative Atrial Fibrillation After Cardiac Surgery: Systematic Review and Meta-analysis.心脏手术后围手术期心房颤动患者发生中风的短期和长期风险:系统评价和荟萃分析
CJC Open. 2021 Sep 16;4(1):85-96. doi: 10.1016/j.cjco.2021.09.011. eCollection 2022 Jan.
8
A Review of Risk Factors and Predictors for Hemorrhagic Transformation in Patients with Acute Ischemic Stroke.急性缺血性脑卒中患者出血转化的危险因素及预测因素综述
Int J Vasc Med. 2021 Dec 6;2021:4244267. doi: 10.1155/2021/4244267. eCollection 2021.
9
Pre-Stroke Statin Therapy Improves In-Hospital Prognosis Following Acute Ischemic Stroke Associated with Well-Controlled Nonvalvular Atrial Fibrillation.卒中前他汀类药物治疗可改善急性缺血性卒中合并控制良好的非瓣膜性心房颤动患者的院内预后。
J Clin Med. 2021 Jul 8;10(14):3036. doi: 10.3390/jcm10143036.
10
The Impact of Age on Mortality and Disability in Patients With Ischemic Stroke Who Underwent Cerebral Reperfusion Therapy: A Brazilian Cohort Study.年龄对接受脑再灌注治疗的缺血性中风患者死亡率和残疾率的影响:一项巴西队列研究。
Front Aging Neurosci. 2021 Jul 6;13:649902. doi: 10.3389/fnagi.2021.649902. eCollection 2021.

缺血性脑卒中患者短期死亡率的预测因素。

Predictors of Short-Term Mortality in Patients with Ischemic Stroke.

机构信息

Department of Neurosciences, "Iuliu Haţieganu" University of Medicine and Pharmacy, 8 Victor Babeş Street, 400012 Cluj-Napoca, Romania.

Department of Pharmacology, Toxicology and Clinical Pharmacology, "Iuliu Haţieganu" University of Medicine and Pharmacy, 23 Gheorghe Marinescu Street, 400337 Cluj-Napoca, Romania.

出版信息

Medicina (Kaunas). 2023 Jun 13;59(6):1142. doi: 10.3390/medicina59061142.

DOI:10.3390/medicina59061142
PMID:37374346
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10304635/
Abstract

: The purpose of this study is to investigate the predictive factors for intrahospital mortality in ischemic stroke patients. We will examine the association between a range of clinical and demographic factors and intrahospital mortality, including age, sex, comorbidities, laboratory values, and medication use. : This retrospective, longitudinal, analytic, observational cohort study included 243 patients over 18 years old with a new ischemic stroke diagnosis who were hospitalized in Cluj-Napoca Emergency County Hospital. Data collected included the patient demographics, baseline characteristics at hospital admission, medication use, carotid artery Doppler ultrasound, as well as cardiology exam, and intrahospital death. : Multivariate logistic regression was used to determine which variables were independently associated with intrahospital death. An NIHSS score > 9 (OR-17.4; < 0.001) and a lesion volume > 22.3 mL (OR-5.8; = 0.003) were found to be associated with the highest risk of death. In contrast antiplatelet treatment (OR-0.349; = 0.04) was associated with lower mortality rates. : Our study identified a high NIHSS score and large lesion volume as independent risk factors for intrahospital mortality in ischemic stroke patients. Antiplatelet therapy was associated with lower mortality rates. Further studies are needed to explore the potential mechanisms underlying these associations and to develop targeted interventions to improve patient outcomes.

摘要

: 本研究旨在探讨缺血性脑卒中患者院内死亡的预测因素。我们将检查一系列临床和人口统计学因素与院内死亡率之间的关联,包括年龄、性别、合并症、实验室值和药物使用。 : 这项回顾性、纵向、分析性、观察性队列研究纳入了 243 名年龄在 18 岁以上的新诊断为缺血性脑卒中且在克卢日-纳波卡紧急县医院住院的患者。收集的数据包括患者人口统计学资料、入院时的基线特征、药物使用情况、颈动脉多普勒超声以及心脏科检查和院内死亡情况。 : 多变量逻辑回归用于确定与院内死亡独立相关的变量。NIHSS 评分>9(OR-17.4; <0.001)和病变体积>22.3 mL(OR-5.8; =0.003)与死亡风险最高相关。相反,抗血小板治疗(OR-0.349; =0.04)与较低的死亡率相关。 : 我们的研究确定了高 NIHSS 评分和大病变体积是缺血性脑卒中患者院内死亡的独立危险因素。抗血小板治疗与较低的死亡率相关。需要进一步研究以探讨这些关联的潜在机制,并制定针对性的干预措施以改善患者预后。