Madian Noha G, El-Ashmanty Basant A, Abdel-Rahim Hadeel K
Biophysics Department, Faculty of Science, Cairo University, Giza 12613, Egypt.
Polymers (Basel). 2023 Jun 6;15(12):2587. doi: 10.3390/polym15122587.
Chitosan is a natural biopolymer that can be used in biomedical applications, tissue engineering, and wound dressing because of its biodegradability, biocompatibility, and antibacterial activity. The blending of chitosan films with natural biomaterials such as cellulose, honey, and curcumin was studied at different concentrations in order to improve their physical properties. Fourier transform infrared (FTIR) spectroscopy, mechanical tensile properties, X-ray diffraction (XRD), antibacterial effects, and scanning electron microscopy (SEM) were studied for all blended films. The XRD, FTIR, and mechanical results showed that films blended with curcumin were more rigid and compatible and had higher antibacterial effects than other blended films. In addition, XRD and SEM showed that blending chitosan films with curcumin decreases the crystallinity of the chitosan matrix compared to cellulose and honey blending films due to increased intermolecular hydrogen bonding, which reduces the close packing of the CS matrix.
壳聚糖是一种天然生物聚合物，因其具有生物可降解性、生物相容性和抗菌活性，可用于生物医学应用、组织工程和伤口敷料。为了改善壳聚糖薄膜的物理性能，研究了壳聚糖薄膜与纤维素、蜂蜜和姜黄素等天然生物材料在不同浓度下的共混情况。对所有共混薄膜进行了傅里叶变换红外（FTIR）光谱、机械拉伸性能、X射线衍射（XRD）、抗菌效果和扫描电子显微镜（SEM）研究。XRD、FTIR和力学结果表明，与姜黄素共混的薄膜比其他共混薄膜更坚硬、相容性更好且具有更高的抗菌效果。此外，XRD和SEM表明，与纤维素和蜂蜜共混薄膜相比，壳聚糖薄膜与姜黄素共混会降低壳聚糖基质的结晶度，这是由于分子间氢键增加，从而减少了壳聚糖基质的紧密堆积。
