Kemble E D, Schultz L A, Thornton A E
Physiol Behav. 1986;37(1):53-6. doi: 10.1016/0031-9384(86)90383-5.
The effect of Fluprazine Hydrochloride (DU 27716) on preference for conspecific male, estrous female and food odors was examined in male rats utilizing a two-compartment choice apparatus. Treatment with 8.0 mg/kg Fluprazine enhanced the preference of males for male odors but had no effect on preference for either estrous female or food odors. The drug-induced enhancement of male odor preference is consistent with the suggestion that Fluprazine interferes in some way with the processing of olfactory stimuli which normally precede offensive attack. The failure of the drug to alter the preference of males for estrous female odors suggests that the increased sniffing of estrous females noted during social testing may be secondary to other sources of conspecific stimulation or may reflect a highly transitory effect on olfactory processes. These results suggest that the suppressive effects of Fluprazine on intermale aggression and copulation are mediated by somewhat distinct mechanisms.
利用双隔室选择装置，在雄性大鼠中研究了盐酸氟哌嗪（DU 27716）对同种雄性、发情期雌性和食物气味偏好的影响。8.0毫克/千克氟哌嗪处理增强了雄性对雄性气味的偏好，但对发情期雌性或食物气味的偏好没有影响。药物诱导的雄性气味偏好增强与以下观点一致：氟哌嗪以某种方式干扰了通常先于攻击性攻击的嗅觉刺激处理。该药物未能改变雄性对发情期雌性气味的偏好，这表明在社交测试期间观察到的对发情期雌性嗅闻增加可能继发于其他同种刺激源，或者可能反映了对嗅觉过程的高度短暂影响。这些结果表明，氟哌嗪对雄性间攻击和交配的抑制作用是由 somewhat distinct 机制介导的。 （注：“somewhat distinct”这里表述不太准确，可能是“ somewhat different”之类的更合适，但按要求未修改直接翻译）
