Basmaeil Saeid M, Suliman Gamaleldin M, Al Garadi Maged A, Al-Badwi Mohammed A, Abdelrahman Mutassim M, Al-Harbi Fahad S, El-Waziry Ahmed M, Alhidary Ibrahim A, Swelum Ayman A
Department of Animal Production, College of Food and Agriculture Science, King Saud University, Riyadh, Saudi Arabia.
Department of Animal and Fish Production, Faculty of Agriculture, Alexandria University, Alexandria, Egypt.
Front Vet Sci. 2023 Jun 12;10:1181426. doi: 10.3389/fvets.2023.1181426. eCollection 2023.
Lasalocid is a feed additive widely used in ruminant nutrition and plays a crucial role in improving livestock productivity, digestibility, immunity, and overall wellbeing. The current study was conducted to investigate the effect of different levels of lasalocid (LAS) supplementation on growth performance, serum biochemistry, ruminal fermentation profile, nutrient digestibility, and gas production of growing goats.
A total of 60 growing Aardi male goats with an average body weight of ~17.12 kg (3-month-old) were used for an 84-day trial. Animals were randomly divided into four treatment groups with 5 replicates of 3 goats each. All four groups were provided with a basal diet supplemented with lasalocid (LAS) at 0 (without supplementation; LAS0), 10 (LAS10), 20 (LAS20), or 30 (LAS30) ppm LAS/kg dry matter (DM). Feed intake was measured weekly, and goats were weighed every 2 weeks for an evaluation of the performance parameters. Blood samples were collected for the measurement of biochemical variables. nutrient digestibility and gas production were evaluated.
The supplementation of LAS at level 30 ppm/kg DM increased ( < 0.05) the body weight gain and average daily gain without linear or quadratic effect. The serum concentrations of high-density lipoprotein were significantly ( < 0.05) higher in the LAS20 group than in other groups with linear and quadratic effects, while low-density lipoprotein concentration was significantly lower in the LAS20 group than in LAS0 and LAS30 with a linear effect. Different levels of lasalocid supplementation had no effect on the ruminal fermentation profile, gas production, and nutrient digestibility. In conclusion, the addition of LAS (20-30 ppm/kg DM) to the goat's diet can improve the growth performance and lipoprotein profile.
拉沙洛西是一种广泛应用于反刍动物营养的饲料添加剂，在提高家畜生产力、消化率、免疫力和整体健康方面发挥着关键作用。本研究旨在探讨不同水平的拉沙洛西（LAS）添加对生长山羊的生长性能、血清生化指标、瘤胃发酵特征、养分消化率和气体产生的影响。
选用60只平均体重约17.12千克（3月龄）的生长阶段阿阿迪雄性山羊进行为期84天的试验。将动物随机分为四个处理组，每组3只山羊，共5个重复。所有四组均给予基础日粮，并分别添加0（不添加；LAS0）、10（LAS10）、20（LAS20）或30（LAS30）ppm LAS/千克干物质（DM）的拉沙洛西。每周测量采食量，每2周对山羊称重以评估性能参数。采集血样以测定生化变量，并评估养分消化率和气体产生情况。
添加30 ppm/千克DM水平的LAS可提高（<0.05）体重增加和平均日增重，且无线性或二次效应。LAS20组的高密度脂蛋白血清浓度显著（<0.05）高于其他组，具有线性和二次效应，而LAS20组的低密度脂蛋白浓度显著低于LAS0和LAS30组，具有线性效应。不同水平的拉沙洛西添加对瘤胃发酵特征、气体产生和养分消化率无影响。总之，在山羊日粮中添加LAS（20 - 30 ppm/千克DM）可改善生长性能和脂蛋白谱。
