Mamo Gabriella, Erickson Stephanie, Komanduri Karthikram, Zayas Dewid, Aggarwal Niti
Internal Medicine, HCA Florida Ocala Hospital, Ocala, USA.
Internal Medicine, University of Central Florida College of Medicine, Orlando, USA.
Cureus. 2023 May 25;15(5):e39472. doi: 10.7759/cureus.39472. eCollection 2023 May.
Infectious mononucleosis (IM) is a clinical syndrome that presents as a triad of fever, pharyngitis, and lymphadenopathy. In most cases, it is caused by the Epstein-Barr virus (EBV), which spreads through upper respiratory secretions, particularly saliva, earning its name as the . In most cases, IM is self-limiting and resolves in two to four weeks without significant sequelae following supportive care. Although rare, IM has been associated with several serious and sometimes life-threatening complications, involving almost any organ system. Splenic infarction is one rare complication of IM due to EBV infection. In the past, IM-induced splenic infarction in the setting of EBV was believed to be rare and mostly limited to patients with underlying hematologic comorbidities. However, we propose this condition to be more common and more likely to occur in individuals without significant medical history than previously suspected. We report a relatively healthy young male patient in his thirties, with no previous history of coagulopathy or complex medical conditions, who was found to have IM-induced splenic infarction.
传染性单核细胞增多症（IM）是一种临床综合征，表现为发热、咽炎和淋巴结病三联征。在大多数情况下，它由 Epstein-Barr 病毒（EBV）引起，该病毒通过上呼吸道分泌物传播，尤其是唾液，因此得名“接吻病”。在大多数情况下，IM 是自限性的，在给予支持性治疗后两到四周内可痊愈，且无明显后遗症。尽管罕见，但 IM 与几种严重且有时危及生命的并发症相关，几乎累及任何器官系统。脾梗死是 EBV 感染引起的 IM 的一种罕见并发症。过去，EBV 感染导致的 IM 相关性脾梗死被认为很罕见，且大多局限于有潜在血液系统合并症的患者。然而，我们认为这种情况比以前怀疑的更为常见，且更有可能发生在无重大病史的个体中。我们报告了一名相对健康的三十多岁年轻男性患者，他既往无凝血功能障碍病史或复杂的内科疾病史，却被发现患有 IM 相关性脾梗死。
