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一名野猪猎人的复发性神经型布鲁氏菌病

Recurrent Neurobrucellosis in a Feral Swine Hunter.

作者信息

Shaw Brian, Madden Melinda, Sanchez Edgar, Carlan Steve

机构信息

Internal Medicine, Orlando Regional Medical Center, Orlando, USA.

Infectious Diseases, Orlando Regional Medical Center, Orlando, USA.

出版信息

Cureus. 2023 May 23;15(5):e39383. doi: 10.7759/cureus.39383. eCollection 2023 May.

Abstract

Brucellosis is a zoonotic infectious disease caused by the bacterial genus and is most commonly transmitted to humans globally via the consumption of contaminated unpasteurized products. In a significant minority of cases, has been found to be transmitted by contact with infected swine bodily fluids such as blood. Only a small proportion of all cases of brucellosis affects the central nervous system, and of the four species of that are known to infect humans, is unusual. Neurologic involvement occurs in a limited proportion of cases and can vary in presentation, ranging from encephalitis to radiculitis or from brain abscess to neuritis. In this case report, we present a 20-year-old male with an eight-day history of headache and neck pain and a high fever that started two days after the onset of the headaches. Three weeks prior, he had hunted, killed, butchered, cooked, and eaten a wild boar in the field. A workup was performed, and blood cultures eventually grew . Although an intensive broad-spectrum antibiotic protocol was implemented, his post-therapy course was complicated. He eventually discontinued his antibiotics after one year.

摘要

布鲁氏菌病是一种由布鲁氏菌属细菌引起的人畜共患传染病,在全球范围内,人类最常通过食用受污染的未经过巴氏杀菌的产品而感染。在极少数情况下,已发现布鲁氏菌病是通过接触受感染猪的体液(如血液)传播的。在所有布鲁氏菌病病例中,只有一小部分会影响中枢神经系统,在已知感染人类的四种布鲁氏菌中,猪布鲁氏菌感染较为罕见。神经系统受累在病例中所占比例有限,表现形式各异,从脑炎到神经根炎,或从脑脓肿到神经炎。在本病例报告中,我们介绍了一名20岁男性,有8天的头痛和颈部疼痛病史,头痛发作两天后开始出现高热。三周前,他在野外猎杀、宰杀、烹饪并食用了一头野猪。进行了相关检查,血培养最终培养出猪布鲁氏菌。尽管实施了强化的广谱抗生素治疗方案,但他治疗后的病程仍很复杂。一年后他最终停用了抗生素。

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