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病例报告:需要体外膜肺氧合的早产儿先天性结核病。

Case Report: Congenital tuberculosis in a premature infant requiring extracorporeal membrane oxygenation.

机构信息

Department of Pediatrics, Division of Critical Care Medicine, University of Alabama at Birmingham, Children's Hospital of Alabama, Birmingham, AL 35233, USA.

Department of Pediatrics, Division of Critical Care Medicine, Duke University Medical Center, Durham, NC 27710, USA.

出版信息

J Extra Corpor Technol. 2023 Jun;55(2):86-90. doi: 10.1051/ject/2023007. Epub 2023 Jun 28.

DOI:10.1051/ject/2023007
PMID:37378441
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10304822/
Abstract

Congenital tuberculosis is a rare infectious disease with less than 500 cases documented worldwide. Mortality is significant, ranging from 34 to 53%, and death without treatment is inevitable. Patients exhibit nonspecific symptoms such as fever, cough, respiratory distress, feeding intolerance, and irritability which can make appropriate diagnosis challenging in Peng et al. (2011) Pediatr Pulmonol 46(12), 1215-1224. Tuberculosis prevalence is particularly high in developing countries where access to resources can be limited in World Health Organization (2019) Global tuberculosis report 2019, Geneva. We present a 2.4-kg premature male infant with acute respiratory distress syndrome secondary to congenital tuberculosis caused by Mycobacterium bovis and tuberculosis-immune reconstitution inflammatory syndrome who was successfully supported with veno-arterial extracorporeal membrane oxygenation.

摘要

先天性结核病是一种罕见的传染病,全世界记录的病例不到 500 例。死亡率很高,范围在 34%至 53%之间,如果不治疗,死亡是不可避免的。患儿表现出非特异性症状,如发热、咳嗽、呼吸窘迫、喂养不耐受和烦躁不安,这使得在 Peng 等人(2011)的研究中,正确诊断具有挑战性。儿科肺脏学杂志 46(12), 1215-1224。在发展中国家,结核病的患病率特别高,在那里,资源的获取可能受到限制,世界卫生组织(2019)全球结核病报告 2019,日内瓦。我们报告了一例 2.4 公斤的早产儿男性,因牛分枝杆菌引起的先天性结核病导致急性呼吸窘迫综合征和结核病免疫重建炎症综合征,成功地接受了静脉-动脉体外膜氧合治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efd3/10304822/ff4388252ff3/ject-55-86-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efd3/10304822/02bc4be67dc5/ject-55-86-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efd3/10304822/ff4388252ff3/ject-55-86-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efd3/10304822/02bc4be67dc5/ject-55-86-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efd3/10304822/ff4388252ff3/ject-55-86-fig2.jpg

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本文引用的文献

1
Cardiohelp System use in school age children and adolescents at a center with interfacility mobile extracorporeal membrane oxygenation capability.心肺辅助系统在具有联网移动体外膜肺氧合能力的中心用于学龄儿童和青少年。
Int J Artif Organs. 2022 Feb;45(2):134-139. doi: 10.1177/0391398821990659. Epub 2021 Feb 2.
2
Tuberculosis-immune reconstitution inflammatory syndrome.结核免疫重建炎性综合征
J Clin Tuberc Other Mycobact Dis. 2016 Mar 11;3:6-9. doi: 10.1016/j.jctube.2016.03.002. eCollection 2016 May.
3
Congenital Tuberculosis in a Neonate: A Case Report and Literature Review.
新生儿先天性结核病:一例报告及文献综述
Front Pediatr. 2019 Jun 21;7:255. doi: 10.3389/fped.2019.00255. eCollection 2019.
4
Hypoxia and Complications of Oxygenation in Extracorporeal Membrane Oxygenation.体外膜肺氧合中的缺氧与氧合并发症
J Cardiothorac Vasc Anesth. 2019 May;33(5):1375-1381. doi: 10.1053/j.jvca.2018.05.028. Epub 2018 Jun 6.
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Pediatric Extracorporeal Membrane Oxygenation.小儿体外膜肺氧合
Crit Care Clin. 2017 Oct;33(4):825-841. doi: 10.1016/j.ccc.2017.06.005. Epub 2017 Jul 29.
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Pediatric Extracorporeal Life Support Organization Registry International Report 2016.《2016年儿科体外生命支持组织国际注册报告》
ASAIO J. 2017 Jul/Aug;63(4):456-463. doi: 10.1097/MAT.0000000000000603.
7
A Perspective of the Diagnosis and Management of Congenital Tuberculosis.先天性结核病的诊断与管理视角
J Pathog. 2016;2016:8623825. doi: 10.1155/2016/8623825. Epub 2016 Nov 24.
8
Venoarterial Extracorporeal Life Support for Neonatal Respiratory Failure: Indications and Impact on Mortality.新生儿呼吸衰竭的静脉-动脉体外生命支持:适应证及对死亡率的影响
ASAIO J. 2017 Jul/Aug;63(4):490-495. doi: 10.1097/MAT.0000000000000495.
9
Analysis of 170 cases of congenital TB reported in the literature between 1946 and 2009.分析 1946 年至 2009 年间文献中报道的 170 例先天性结核病病例。
Pediatr Pulmonol. 2011 Dec;46(12):1215-24. doi: 10.1002/ppul.21490. Epub 2011 May 27.
10
Congenital tuberculosis requiring extracorporeal membrane oxygenation.需要体外膜肺氧合的先天性结核病。
Pediatr Pulmonol. 2004 May;37(5):470-3. doi: 10.1002/ppul.10423.