Respiratory Center, Hospital de Niños Dr. Ricardo Gutiérrez, Buenos Aires, Argentina.
Department for Children and Adolescents, Division of Allergology, Pulmonology and Cystic Fibrosis, University Hospital Frankfurt, Goethe University, Frankfurt, Germany.
Pediatr Pulmonol. 2024 Sep;59(9):2338-2348. doi: 10.1002/ppul.26570. Epub 2023 Jun 28.
Postinfectious bronchiolitis obliterans (PiBO) is a rare and severe form of chronic obstructive lung disease caused by an infectious injury to the lower respiratory tract. The most commonly recognized inciting stimuli leading to PiBO are airway pathogens, such as adenovirus and Mycoplasma. PiBO is characterized by persistent and nonreversible airway obstruction, with functional and radiological evidence of small airway involvement. The literature has limited information on the aetiology, clinical profile, treatment, and outcome of PiBO.
感染后细支气管炎闭塞（PiBO）是一种罕见且严重的慢性阻塞性肺疾病，由下呼吸道的感染性损伤引起。最常被识别的导致 PiBO 的激发因素是气道病原体，如腺病毒和支原体。PiBO 的特征是持续且不可逆转的气道阻塞，有小气道受累的功能和影像学证据。文献中关于 PiBO 的病因、临床特征、治疗和结局的信息有限。
