Wei Qing, Liu Jing, Chen Xun, Li Chunyan, Nong Guangmin, Li Yan
Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Department of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Front Pediatr. 2025 Aug 21;13:1590800. doi: 10.3389/fped.2025.1590800. eCollection 2025.
Virus infection is a common cause of lung injury and can result in lung fibrosis in severe cases. Furthermore, it is a significant trigger of disease exacerbation in patients with lung fibrosis. However, nearly all the case reports or case series to date have focused on the adult population rather than the pediatric population. Here, we report three cases of virus infection-induced exacerbations of lung injury and fibrosis in children with diffuse alveolar hemorrhage. To our knowledge, this is one of the first articles to report virus infection-induced lung injury and fibrosis in children.
病毒感染是肺损伤的常见原因，严重时可导致肺纤维化。此外，它是肺纤维化患者疾病加重的重要诱因。然而，迄今为止，几乎所有的病例报告或病例系列都集中在成人而非儿童群体。在此，我们报告三例病毒感染诱发弥漫性肺泡出血患儿肺损伤和纤维化加重的病例。据我们所知，这是首批报道儿童病毒感染诱发肺损伤和纤维化的文章之一。
