Department of Echocardiography of The Third Affiliated Hospital of Soochow University, Chang Zhou NO.1 Hospital, Chang Zhou City, Jiangsu Province, China.
Department of Cardiovascular Division of The Third Affiliated Hospital of Soochow University, Chang Zhou NO.1 Hospital, Chang Zhou City, Jiangsu Province, China.
J Clin Hypertens (Greenwich). 2023 Jul;25(7):638-646. doi: 10.1111/jch.14692. Epub 2023 Jun 28.
To assess the value of electrocardiogram (ECG) RV5/V6 criteria for diagnosing left ventricular hypertrophy (LVH) in marathons. A total of 112 marathon runners who met the requirements for "Class A1" events certified by the Chinese Athletics Association in Changzhou City were selected, and their general clinical information was collected. ECG examinations were performed using a Fukuda FX7402 Cardimax Comprehensive Electrocardiograph Automatic Analyser, whereas routine cardiac ultrasound examinations were performed using a Philips EPIQ 7C echocardiography system. Real-time 3-dimensional echocardiography (RT-3DE) was performed to acquire 3-dimensional images of the left ventricle and to calculate the left ventricular mass index (LVMI). According to the LVMI criteria of the American Society of Echocardiography for the diagnosis of LVH, the participants were divided into an LVMI normal group (n = 96) and an LVH group (n = 16). The correlation between the ECG RV5/V6 criteria and LVH in marathon runners was analysed using multiple linear regression stratified by sex and compared with the Cornell (SV3 + RaVL), modified Cornell (SD + RaVL), Sokolow-Lyon (SV1 + RV5/V6), Peguero-Lo Presti (SD + SV4), SV1, SV3, SV4, and SD criteria. In marathon runners, the ECG parameters SV3 + RaVL, SD + RaVL, SV1 + RV5/V6, SD + SV4, SV3, SD, and RV5/V6 were able to identify LVH (all p < .05). When stratified by sex, linear regression analysis revealed that a significantly higher number of ECG RV5/V6 criteria were evident in the LVH group than in the LVMI normal group (p < .05), both with no adjustment and after initial adjustment (including age and body mass index), as well as after full adjustment (including age, body mass index, interventricular septal thickness, left ventricular end-diastolic diameter, left ventricular posterior wall thickness, and history of hypertension). Additionally, curve fitting showed that the ECG RV5/V6 values increased with increasing LVMI in marathon runners, exhibiting a nearly linear positive correlation. In conclusions, the ECG RV5/V6 criteria were correlated with LVH in marathon runners.
评估心电图（ECG）RV5/V6 标准在马拉松运动员中诊断左心室肥厚（LVH）的价值。在常州市，共选择了 112 名符合中国田径协会“ A1 级”赛事要求的马拉松运动员，收集了他们的一般临床信息。使用 Fukuda FX7402 Cardimax 综合心电图自动分析仪进行心电图检查，使用 Philips EPIQ 7C 超声心动图系统进行常规心脏超声检查。使用实时 3 维超声心动图（RT-3DE）获取左心室的 3 维图像，并计算左心室质量指数（LVMI）。根据美国超声心动图学会诊断 LVH 的 LVMI 标准，将参与者分为 LVMI 正常组（n=96）和 LVH 组（n=16）。采用多线性回归分析性别分层的心电图 RV5/V6 标准与马拉松运动员 LVH 的相关性，并与 Cornell（SV3+RaVL）、改良 Cornell（SD+RaVL）、Sokolow-Lyon（SV1+RV5/V6）、Peguero-Lo Presti（SD+SV4）、SV1、SV3、SV4 和 SD 标准进行比较。在马拉松运动员中，心电图参数 SV3+RaVL、SD+RaVL、SV1+RV5/V6、SD+SV4、SV3、SD 和 RV5/V6 能够识别 LVH（均 p<0.05）。按性别分层后，线性回归分析显示，LVH 组的心电图 RV5/V6 标准明显高于 LVMI 正常组（均 p<0.05），且未经调整和初始调整（包括年龄和体重指数）后，以及完全调整后（包括年龄、体重指数、室间隔厚度、左心室舒张末期直径、左心室后壁厚度和高血压病史）。此外，曲线拟合显示，心电图 RV5/V6 值随马拉松运动员 LVMI 的增加而增加，呈近线性正相关。综上所述，心电图 RV5/V6 标准与马拉松运动员的 LVH 相关。
