Strel'nikov Iu E, Libikova N I, Milevskiĭ E I, Sharova L A
Radiobiologiia. 1986 May-Jun;26(3):323-8.
It was shown that different polysaccharides markedly vary in their toxicity, exert a radioprotective effect when administered both 24 h and 1-4 h before irradiation, enhance and prolong the radioprotective action of S-containing radioprotective agents, and inhibit DNA synthesis in bone marrow which, in all appearance, plays a certain role in the mechanism of their radioprotective action.
结果表明,不同的多糖在毒性上有显著差异,在照射前24小时和1 - 4小时给药时均具有辐射防护作用,能增强并延长含硫辐射防护剂的辐射防护作用,且抑制骨髓中的DNA合成,这在其辐射防护作用机制中显然起到一定作用。