Generali Matteo, Annunziata Gianluca, Pirillo Debora, D'Ippolito Giovanni, Ciarlini Gino, Aguzzoli Lorenzo, Mandato Vincenzo Dario
Unit of Obstetrics and Gynaecologic Oncology, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Front Med (Lausanne). 2023 Jun 14;10:1196496. doi: 10.3389/fmed.2023.1196496. eCollection 2023.
The aim of this narrative review is to summarize the available evidence on the use of minimal invasive surgery (MIS) in the management of epithelial ovarian cancer (EOC).
MIS is currently performed to stage and treat EOC at different stage of presentation. We will evaluate risks and benefits of minimally invasive surgery for early stage EOC treatment, then potential advantages provided by staging laparoscopy in identifying patients suitable for primary cytoreductive surgery (PDS) will be discussed. Finally we will investigate the growing role of MIS in the treatment of advanced EOC after neoadjuvant chemotherapy (NACT) and in the treatment of EOC recurrence.
An electronic database search was performed on PubMed, Medline, and Google Scholar for relevant studies up to December 2022.
LPS represents a feasible surgical procedure for the staging and treatment in early, advanced and EOC relapse in selected patients treated in high-volume oncological centers by surgeons with adequate experience in advanced surgical procedures. Despite the increasing use of MIS over the last few years, randomized clinical trials are still needed to prove its effectiveness.
本叙述性综述的目的是总结关于微创手术(MIS)用于上皮性卵巢癌(EOC)管理的现有证据。
目前进行MIS是为了对不同分期表现的EOC进行分期和治疗。我们将评估早期EOC治疗中微创手术的风险和益处,然后讨论分期腹腔镜检查在识别适合原发性细胞减灭术(PDS)的患者方面提供的潜在优势。最后,我们将研究MIS在新辅助化疗(NACT)后晚期EOC治疗以及EOC复发治疗中的作用日益增加的情况。
在PubMed、Medline和谷歌学术上进行电子数据库检索,以查找截至2022年12月的相关研究。
对于在大型肿瘤中心由具有足够先进手术经验的外科医生治疗的选定患者,腹腔镜分期手术(LPS)是早期、晚期EOC分期及复发治疗的一种可行手术方法。尽管在过去几年中MIS的使用越来越多,但仍需要随机临床试验来证明其有效性。