Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, Hunan, China.
Hunan Provincial Key Laboratory of Clinical Epidemiology, Changsha, Hunan, China.
Psychiatr Q. 2023 Sep;94(3):371-383. doi: 10.1007/s11126-023-10040-z. Epub 2023 Jun 30.
This study aimed to investigate the prevalence of anxiety and its associated factors among inpatients with type 2 diabetes mellitus (T2DM) in China. This study was a cross-sectional study. Inpatients with T2DM admitted to the Endocrinology Department of Xiangya Hospital, Central South University in Hunan Province of China from March 2021 to December 2021 were consecutively included in this study. Participants were interviewed to obtain the data on socio-demographic characteristics, lifestyle characteristics, T2DM-related information, and social support. Anxiety was measured using the Hospital Anxiety and Depression Scale-anxiety subscale by experienced physicians. Multivariable logistic regression analysis was used to estimate the independent contribution of each independent variable to anxiety. A total of 496 inpatients with T2DM were included in this study. The prevalence of anxiety was 21.8% (95% confidence interval [CI]: 18.1%-25.4%). The results of multivariable logistic regression analysis indicated that age of at least 60 (adjusted odd ratio [aOR] = 1.79, 95% CI: 1.04-3.08), and having diabetes specific complications (aOR = 4.78, 95% CI: 1.02-22.44) were risk factors for anxiety, and an educational level of high school or above (aOR = 0.55, 95% CI: 0.31-0.99), regular physical activity (aOR = 0.36, 95% CI: 0.22-0.58), and high social support (aOR = 0.30, 95% CI: 0.17-0.53) were protective factors for anxiety. A predictive model based on these five variables showed good performance (area under the curve = 0.80). Almost one in five inpatients with T2DM suffered from anxiety in China. Age, educational level, regular physical activity, diabetes specific complications, and social support were independently associated with anxiety.
本研究旨在调查中国 2 型糖尿病（T2DM）住院患者焦虑的患病率及其相关因素。这是一项横断面研究。连续纳入 2021 年 3 月至 2021 年 12 月期间在中国湖南省中南大学湘雅医院内分泌科住院的 T2DM 患者。通过经验丰富的医生使用医院焦虑和抑郁量表-焦虑分量表对参与者进行访谈，以获取社会人口统计学特征、生活方式特征、T2DM 相关信息和社会支持的数据。采用多变量逻辑回归分析估计每个自变量对焦虑的独立贡献。共有 496 例 T2DM 住院患者纳入本研究。焦虑的患病率为 21.8%（95%置信区间[CI]：18.1%-25.4%）。多变量逻辑回归分析的结果表明，年龄至少 60 岁（调整后的优势比[aOR] = 1.79，95%CI：1.04-3.08）和患有糖尿病特异性并发症（aOR = 4.78，95%CI：1.02-22.44）是焦虑的危险因素，而高中及以上教育程度（aOR = 0.55，95%CI：0.31-0.99）、有规律的体育活动（aOR = 0.36，95%CI：0.22-0.58）和高社会支持（aOR = 0.30，95%CI：0.17-0.53）是焦虑的保护因素。基于这五个变量的预测模型表现出良好的性能（曲线下面积 = 0.80）。在中国，近五分之一的 T2DM 住院患者患有焦虑症。年龄、教育程度、有规律的体育活动、糖尿病特异性并发症和社会支持与焦虑症独立相关。
