Robinson Andrea, von Kleeck B Wade, Gayzik F Scott
Wake Forest University School of Medicine, Department of Biomedical Engineering, United States.
Wake Forest University School of Medicine, Department of Biomedical Engineering, United States.
Accid Anal Prev. 2023 Sep;190:107182. doi: 10.1016/j.aap.2023.107182. Epub 2023 Jun 28.
No vehicle testing standard (physical or computational) employs a mid-sized female human surrogate, despite discrepancies related to injury outcomes for female occupants amongst all vehicle users. We detail the design and preliminary validation of 50th percentile female (F50) computational human body models (HBMs) based on Global Human Body Models Consortium (GHBMC) models.
Data for the target geometry was collected as part of the initial generation of GHBMC models. Imaging, surface data, and 15 anthropomorphic measures from a living female subject (60.8 kg and 1.61 m) served as the baseline for model development. Due to the role rib cage geometry plays in biomechanical loading, rib cage morphology from secondary retrospective data was leveraged to identify an average female rib cage based on gross anatomical features. A female rib cage was selected from an existing dataset closest to the mean depth, height, and width of the set, considering only those aged 20 - 50 years. The selected subject among this secondary set also exhibited a 7th rib angle and sternum angle within 5% of the mean measurements, and within the range of previously reported studies. The GHBMC 5th percentile, small female detailed (high biofidelity) and simplified (computationally efficient) models were morphed to match the F50 subject body surface, selected bones, and mean rib cage using established thin plate spline techniques. The models were validated vs. previously published literature studies with an emphasis on rib cage response. Model data was compared to 47 channels of experimental data across four biomechanical hub simulations, two sled test simulations (one of which included all female PMHS), and two robustness simulations to test stability. Model results were mass scaled to the average of the reported corridors. Objective evaluation was conducted using CORA. IRB approval was obtained for all prospective and retrospective data collected or used. The target rib cage was selected from retrospective image data used in prior studies (n = 339 chest CT scans).
The morphed HBMs closely matched the target geometry. The detailed and simplified models had masses and element counts of 61.2 kg and 61.8 kg, and 2.8 million and 0.3 million, respectively. The mass difference is due to a coarser mesh in the simplified model. The simplified model ran 23 times faster than the detailed model on the same hardware. Each model exhibited stability in robustness tests, and the average CORA scores were 0.80 and 0.72 in the detailed and simplified models, respectively. The models performed well in frontal impacts against PMHS corridors after mass scaling.
Numerous recent studies underscore poorer injury outcomes for female vehicle occupants compared to males. While such outcomes are multifactorial, the average female models introduced in this work offer a novel tool within a widely used family of HBMs to reduce the outcome gap in terms of injury for all drivers. HBMs can be deployed in safety studies or in future regulatory requirements faster and more economically than a resized or newly designed ATDs aimed at the same target population.
尽管在所有车辆使用者中,女性驾乘者的损伤结果存在差异,但尚无车辆测试标准(物理或计算方面)采用中等身材的女性人体模型。我们详细介绍了基于全球人体模型联盟(GHBMC)模型的第50百分位女性(F50)计算人体模型(HBM)的设计和初步验证。
作为GHBMC模型初始生成的一部分,收集了目标几何形状的数据。来自一名在世女性受试者(60.8千克,身高1.61米)的成像、表面数据和15项人体测量数据作为模型开发的基线。由于胸廓几何形状在生物力学负荷中所起的作用,利用二次回顾性数据中的胸廓形态,根据大体解剖特征确定平均女性胸廓。从现有数据集中选择一个最接近该组平均深度、高度和宽度的女性胸廓,仅考虑年龄在20至50岁之间的个体。在这个二次数据集中选择的受试者,其第7肋角度和胸骨角度也在平均测量值的5%以内,且在先前报道的研究范围内。使用既定的薄板样条技术,将GHBMC第5百分位的小型女性详细(高生物保真度)模型和简化(计算高效)模型进行变形,以匹配F50受试者的身体表面、选定骨骼和平均胸廓。通过与先前发表的文献研究进行对比来验证模型,重点是胸廓反应。将模型数据与四个生物力学枢纽模拟、两个雪橇试验模拟(其中一个包括所有女性人体尸体标本(PMHS))以及两个用于测试稳定性的稳健性模拟中的47个通道的实验数据进行比较。将模型结果按质量缩放到报告通道的平均值。使用CORA进行客观评估。对于所有收集或使用的前瞻性和回顾性数据均获得了机构审查委员会(IRB)的批准。目标胸廓是从先前研究中使用的回顾性图像数据(n = 339例胸部CT扫描)中选择的。
变形后的HBM与目标几何形状紧密匹配。详细模型和简化模型的质量分别为61.2千克和61.8千克,单元数量分别为280万个和30万个。质量差异是由于简化模型中的网格较粗。在相同硬件上,简化模型的运行速度比详细模型快23倍。每个模型在稳健性测试中均表现出稳定性,详细模型和简化模型的平均CORA分数分别为0.80和0.72。在质量缩放后,模型在与PMHS通道的正面碰撞中表现良好。
最近的大量研究强调,与男性相比,女性车辆驾乘者的损伤结果更差。虽然这些结果是多因素导致的,但本研究中引入的平均女性模型在广泛使用的HBM系列中提供了一种新工具,以缩小所有驾驶员在损伤方面的结果差距。与针对相同目标人群重新调整尺寸或新设计的人体试验假人(ATD)相比,HBM可更快、更经济地应用于安全研究或未来的监管要求中。