Retraction Note: Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice.
作者信息
Afridi Ruqayya, Khan Ashraf Ullah, Khalid Sidra, Shal Bushra, Rasheed Hina, Ullah Muhammad Zia, Shehzad Omer, Kim Yeong Shik, Khan Salman
机构信息
Department of Pharmacy, Faculty of Biological Sciences, Quaid-I-Azam University, Islamabad, Pakistan.
Department of Pharmacy, Abdul Wali Khan University, Mardan, Pakistan.
出版信息
BMC Pharmacol Toxicol. 2023 Jun 30;24(1):39. doi: 10.1186/s40360-023-00679-6.
Abstract
摘要
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Retraction Note: Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice.撤回说明：黄烷酮衍生物枳属苷在小鼠急性和慢性炎症性疼痛模型中的抗痛觉过敏特性。
BMC Pharmacol Toxicol. 2023 Jun 30;24(1):39. doi: 10.1186/s40360-023-00679-6.
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Biomol Ther (Seoul). 2020 Jul 1;28(4):337-343. doi: 10.4062/biomolther.2018.216.
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Poncirin Induces Apoptosis in AGS Human Gastric Cancer Cells through Extrinsic Apoptotic Pathway by up-Regulation of Fas Ligand.枳苷通过上调Fas配体，经外源性凋亡途径诱导AGS人胃癌细胞凋亡。
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Poncirin promotes osteoblast differentiation but inhibits adipocyte differentiation in mesenchymal stem cells.蓬皮辛可促进间充质干细胞中的成骨细胞分化，但抑制脂肪细胞分化。
Eur J Pharmacol. 2011 Aug 16;664(1-3):54-9. doi: 10.1016/j.ejphar.2011.04.047. Epub 2011 May 1.
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Poncirin attenuates CCL4-induced liver injury through inhibition of oxidative stress and inflammatory cytokines in mice.蓬皮辛通过抑制氧化应激和炎症细胞因子减轻 CCL4 诱导的小鼠肝损伤。
BMC Complement Med Ther. 2020 Apr 19;20(1):115. doi: 10.1186/s12906-020-02906-7.
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Poncirin, an orally active flavonoid exerts antidiabetic complications and improves glucose uptake activating PI3K/Akt signaling pathway in insulin resistant C2C12 cells with anti-glycation capacities.蓬皮辛是一种具有口服活性的类黄酮，具有抗糖尿病并发症的作用，并能改善葡萄糖摄取，在具有抗糖化能力的胰岛素抵抗 C2C12 细胞中通过激活 PI3K/Akt 信号通路来实现。
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Therapeutic Potential of Poncirin Against Numerous Human Health Complications: Medicinal Uses and Therapeutic Benefit of an Active Principle of Citrus Species.朴地红对多种人类健康并发症的治疗潜力：柑橘属植物活性成分的药用用途和治疗益处。
Endocr Metab Immune Disord Drug Targets. 2021;21(11):1974-1981. doi: 10.2174/1871530321666210108122924.
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Inhibition of LPS-induced iNOS, COX-2 and cytokines expression by poncirin through the NF-kappaB inactivation in RAW 264.7 macrophage cells.枳苷通过使RAW 264.7巨噬细胞中的核因子κB失活来抑制脂多糖诱导的诱导型一氧化氮合酶、环氧化酶-2和细胞因子的表达。
Biol Pharm Bull. 2007 Dec;30(12):2345-51. doi: 10.1248/bpb.30.2345.
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Poncirin downregulates ATP-binding cassette transporters to enhance cisplatin sensitivity in cisplatin-resistant osteosarcoma cells.蓬胆素通过下调三磷酸腺苷结合盒转运蛋白来增强耐顺铂骨肉瘤细胞对顺铂的敏感性。
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Poncirin and its metabolite ponciretin attenuate colitis in mice by inhibiting LPS binding on TLR4 of macrophages and correcting Th17/Treg imbalance.枳属苷及其代谢产物枳属苷元通过抑制脂多糖与巨噬细胞Toll样受体4（TLR4）的结合以及纠正辅助性T细胞17（Th17）/调节性T细胞（Treg）失衡来减轻小鼠结肠炎。
J Ethnopharmacol. 2016 Aug 2;189:175-85. doi: 10.1016/j.jep.2016.05.044. Epub 2016 May 17.
本文引用的文献
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Anti-inflammatory, anti-rheumatic and analgesic activities of 2-(5-mercapto-1,3,4-oxadiazol-2-yl)-N-propylbenzenesulphonamide (MOPBS) in rodents.2-(5-巯基-1,3,4-恶二唑-2-基)-N-丙基苯磺酰胺（MOPBS）在啮齿动物中的抗炎、抗风湿和镇痛活性。
Inflammopharmacology. 2018 Aug;26(4):1037-1049. doi: 10.1007/s10787-018-0446-4. Epub 2018 Feb 22.
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