初产妇中轻度和重度子痫前期的差异趋势：一项基于韩国人群的研究
Differential trend of mild and severe preeclampsia among nulliparous women: a population-based study of South Korea.
作者信息
Kim Seyoung, Lee Ji Yeon, Kim Taemi, Gwak Eunseon, Choe Seung-Ah
机构信息
Department of Public Health Science, Graduate School of Public Health, Seoul National University, Seoul, Korea.
Department of Obstetrics and Gynecology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea.
出版信息
Obstet Gynecol Sci. 2023 Sep;66(5):449-454. doi: 10.5468/ogs.23033. Epub 2023 Jun 29.
We explored the annual risks of mild and severe preeclampsia (PE) among nulliparous women. Using the National Health Information Database of South Korea, 1,317,944 nulliparous women who gave live births were identified. Mild PE increased from 0.9% in 2010 to 1.4% in 2019 (P for trend=0.006), while severe PE decreased from 0.4% in 2010 to 0.3% in 2019 (P=0.049). The incidence of all types of PE (mild and severe) showed no linear change (P=0.514). Adjusted odds ratio (OR) of severe PE decreased in 2013 (0.68; 95% confidence interval [CI]: 0.60, 0.77) and beyond compared to that in 2010, while the OR of mild PE increased in 2017 (1.14; 95% CI: 1.06, 1.22) and beyond. Mild PE was found to be less likely to progress to the severe form since 2010; however, the overall risk of PE among women did not change.
我们探讨了初产妇发生轻度和重度子痫前期（PE）的年度风险。利用韩国国家健康信息数据库，确定了1317944例分娩活产的初产妇。轻度PE从2010年的0.9%增至2019年的1.4%（趋势P=0.006），而重度PE从2010年的0.4%降至2019年的0.3%（P=0.049）。所有类型PE（轻度和重度）的发病率无线性变化（P=0.514）。与2010年相比，2013年及以后重度PE的校正比值比（OR）降低（0.68；95%置信区间[CI]：0.60，0.77），而轻度PE的OR在2017年及以后升高（1.14；95%CI：1.06，1.22）。自2010年以来，轻度PE进展为重度形式的可能性较小；然而，女性中PE的总体风险没有变化。
Zotero 插件