性别对腹疝修补术结果的影响：一项系统评价和荟萃分析。
Impact of sex on ventral hernia repair outcomes: A systematic review and meta-analysis.
作者信息
Oliveira Eduarda Sabá C, Calvi Izabela P, Hora David A B, Gomes Cintia P, Burlá Marina M, Mao Rui-Min Diana, de Figueiredo Sergio Mazzola Poli, Lu Richard
机构信息
Division of Medicine, University of Brasilia, Brasilia, Distrito Federal, Brazil.
Division of Medicine, Immanuel Kant Baltic Federal University, Kaliningrad, Kaliningrad Oblast, Russian Federation.
出版信息
Am J Surg. 2023 Sep;226(3):385-392. doi: 10.1016/j.amjsurg.2023.06.026. Epub 2023 Jun 29.
BACKGROUND
Given the variability in abdominal physiology and hernia presentation between sexes, better comprehension of sex-related differences in outcomes would tailor surgical approach and counseling regarding postoperative outcomes. This meta-analysis aims to appraise the effect of sex on the outcomes of ventral hernia repair.
METHODS
A literature search in PubMed, EMBASE and Cochrane selected studies comparing outcomes of ventral hernia repair between sexes. Postoperative outcomes were assessed by pooled and meta-analysis. Statistical analysis was performed using RevMan 5.4.
RESULTS
We screened 3128 studies, reviewed 133, and included 18 observational studies, which encompassed 220,799 patients following ventral hernia repair. Postoperative chronic pain was significantly higher in female (OR 1,9; 95% CI 1,64-2,2; p < 0,001). There were no significant differences in complications, readmission, or recurrence rates between females and males.
CONCLUSION
Female sex is associated with a higher risk of postoperative chronic pain following ventral hernia repair.
背景
鉴于男女腹部生理和疝表现存在差异，更好地理解与性别相关的预后差异将有助于调整手术方式并提供有关术后结果的咨询。本荟萃分析旨在评估性别对腹疝修补术预后的影响。
方法
在PubMed、EMBASE和Cochrane数据库中进行文献检索，筛选比较男女腹疝修补术预后的研究。通过汇总和荟萃分析评估术后结果。使用RevMan 5.4进行统计分析。
结果
我们筛选了3128项研究，审查了133项，纳入了18项观察性研究，这些研究涵盖了220799例接受腹疝修补术的患者。女性术后慢性疼痛明显更高（OR 1.9；95%CI 1.64 - 2.2；p < 0.001）。女性和男性在并发症、再入院率或复发率方面没有显著差异。
结论
女性在腹疝修补术后发生慢性疼痛的风险较高。
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