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miR-126-5p affects the chemosensitivity of colorectal cancer cells by regulating , ERK1/2 pathway and apoptosis.

作者信息

Xu Mingshi, Zhang Gang, Gu Xiaofan, Zhao Fangqin, Yang Zhongmin, Zhang Xiongwen

机构信息

Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200241, China.

出版信息

Genes Dis. 2022 Jun 4;10(3):675-678. doi: 10.1016/j.gendis.2022.05.024. eCollection 2023 May.

DOI:10.1016/j.gendis.2022.05.024
PMID:37396522
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10308090/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eb7/10308090/31428d83498e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eb7/10308090/31428d83498e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eb7/10308090/31428d83498e/gr1.jpg

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本文引用的文献

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Long intergenic noncoding RNA 00665 promotes proliferation and inhibits apoptosis in colorectal cancer by regulating miR-126-5p.长链非编码 RNA 00665 通过调控 miR-126-5p 促进结直肠癌细胞增殖并抑制其凋亡。
Aging (Albany NY). 2021 Apr 20;13(10):13571-13584. doi: 10.18632/aging.202874.
2
SPRED proteins and their roles in signal transduction, development, and malignancy.SPRED 蛋白及其在信号转导、发育和恶性肿瘤中的作用。
Genes Dev. 2020 Nov 1;34(21-22):1410-1421. doi: 10.1101/gad.341222.120.
3
SPRED1 deletion confers resistance to MAPK inhibition in melanoma.
SPRED1 缺失赋予黑色素瘤对 MAPK 抑制的抗性。
J Exp Med. 2021 Mar 1;218(3). doi: 10.1084/jem.20201097.
4
YAP1-induced MALAT1 promotes epithelial-mesenchymal transition and angiogenesis by sponging miR-126-5p in colorectal cancer.YAP1 诱导的 MALAT1 通过海绵吸附 miR-126-5p 促进结直肠癌细胞的上皮-间充质转化和血管生成。
Oncogene. 2019 Apr;38(14):2627-2644. doi: 10.1038/s41388-018-0628-y. Epub 2018 Dec 10.
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EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer.急诊医师、癌症干细胞和耐药性：抗癌之战中的新兴邪恶轴心。
Oncogene. 2010 Aug 26;29(34):4741-51. doi: 10.1038/onc.2010.215. Epub 2010 Jun 7.