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一名年轻女性患者的罕见骨化性外毛根鞘囊肿:病例报告及文献综述

A rare ossifying trichilemmal cyst in a young female patient: a case report and literature review.

作者信息

Serpetsidaki Evanthia, Gkionis Ioannis G, Arvelaki Roxani N, Karafoulidou Zafeiro I, Dimou Anastasios F, Kafousi Maria

机构信息

Faculty of Medicine, National and Kapodistrian University of Athens.

Department of General Surgery, Venizeleio General Hospital, Heraklion, Crete.

出版信息

Dermatol Reports. 2022 Sep 16;15(2):9569. doi: 10.4081/dr.2022.9569. eCollection 2023 Jun 7.

Abstract

Trichilemmal cysts (TCs) constitute the second most common cutaneous cysts and are mostly presented on the scalp of middleaged women. Therefore, it is unusual for a young person to have a TC and it is extremely rare for a TC to be ossified. In the literature, only 8 cases of TCs with concomitant ossification have been described. We report the case of a 22-year-old female who presented with a scalp nodule and was treated via surgical excision of the lesion. The pathology examination of the surgical specimen revealed a lesion consisting of a multilayered squamous epithelium of slightly eosinophilic maturing keratinocytes. There was no granular layer, whereas the core of the lesion was occupied by mature bone tissue with calcium deposits. The definite diagnosis of the pathology report was ossifying TC. The aim of this report is, to enlighten clinicians about this rare pathological entity.

摘要

毛发囊肿(TCs)是第二常见的皮肤囊肿,多见于中年女性头皮。因此,年轻人患毛发囊肿并不常见,而毛发囊肿骨化极为罕见。文献中仅描述了8例伴有骨化的毛发囊肿。我们报告一例22岁女性,因头皮结节就诊,经手术切除病变进行治疗。手术标本的病理检查显示病变由多层鳞状上皮组成,角质形成细胞轻度嗜酸性成熟。无颗粒层,而病变核心被有钙沉积的成熟骨组织占据。病理报告明确诊断为骨化性毛发囊肿。本报告旨在让临床医生了解这种罕见的病理实体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c20/10312109/ef3769182be0/dr-15-2-9569-g001.jpg

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