Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences, Tehran, Iran.
Int J Dermatol. 2020 Apr;59(4):457-462. doi: 10.1111/ijd.14808. Epub 2020 Feb 7.
Benign cutaneous lesions, so-called cysts, are frequently seen in clinics and might evoke cosmetic and psychosocial concerns.
This study aimed to demonstrate the clinicopathologic findings of these lesions and also the importance of histological evaluation for prevention of misdiagnosing a benign-appearing malignant lesion.
A descriptive study was conducted of 2,438 cases who had a diagnosis of cyst confirmed with pathology. The data of patients over the 6-year period between 2011 and 2017, including gender, age, location, prevalence, complications, and microscopic evaluation, were gathered.
From a total of 2,438 records with a clinical diagnosis of mucocutaneous cyst, 2077 had the pathologic diagnosis of cysts. They consisted of 910 women (43.8%) and 1167 men (56.1%) with a mean age of 42. The most common mucocutaneous cysts were epidermal cyst 994 (47.8%) followed by trichilemmal cyst 495 (23.8%). In 479 (19.6%) records, the clinical diagnosis was not congruent with histopathological diagnosis including 45 malignant cases. Basal cell carcinoma in 22 (48.9%) was the most common one.
This study reports on clinical characteristics of cutaneous cysts and the need for a decent diagnostic investigation, like histopathology, for achieving a reliable diagnosis regarding the benign mimicking malignant lesions, especially high risk ones.
良性皮肤病变,即所谓的囊肿,在临床上很常见,可能会引起美容和心理社会方面的关注。
本研究旨在展示这些病变的临床病理表现,以及组织学评估对于防止误诊良性表现的恶性病变的重要性。
对 2011 年至 2017 年期间的 2438 例经病理证实为囊肿的病例进行了描述性研究。收集了 6 年内患者的性别、年龄、部位、患病率、并发症和显微镜评估等数据。
在总共 2438 份有临床诊断为黏膜皮肤囊肿的记录中,有 2077 份的病理诊断为囊肿。其中 910 例为女性(43.8%),1167 例为男性(56.1%),平均年龄为 42 岁。最常见的黏膜皮肤囊肿是表皮囊肿 994 例(47.8%),其次是毛鞘囊肿 495 例(23.8%)。在 479 份(19.6%)记录中,临床诊断与组织病理学诊断不一致,包括 45 例恶性病例。基底细胞癌 22 例(48.9%)最为常见。
本研究报告了皮肤囊肿的临床特征,以及需要进行适当的诊断性检查,如组织病理学检查,以获得可靠的诊断,特别是对于良性类似恶性的病变,尤其是高危病变。