Ekhator Chukwuyem, Rak Ramin
Neuro-Oncology, College of Osteopathic Medicine, New York Institute of Technology, Long Island, USA.
Neurosurgery, Neurosurgical PC (NSPC) Brain and Spine Surgery, Rockville Center, USA.
Cureus. 2023 Jun 28;15(6):e41113. doi: 10.7759/cureus.41113. eCollection 2023 Jun.
The increase in benign spinal tumors among adults over the last decade has been a major cause of concern. This worrisome trend has been attributed to many factors, including improved detection techniques, enhanced access to medical care, and the aging population. The research primarily focuses on Schwannoma, which is a rare type of tumor that arises from Schwann cells, which are responsible for producing the myelin sheath that surrounds and protects nerves. Although the majority of schwannomas are benign, there have been instances where they have transformed into malignant tumors, potentially leading to significant morbidity and mortality. We report a case of a 68-year-old woman who presented with progressive back pain and weakness in both lower limbs over the past months. The pain was initially localized to the lower back but gradually intensified and radiated down to the legs. The patient reported difficulty walking and a sensation of tingling and numbness in the feet. She denied any recent trauma or significant medical history. On physical examination, there was reduced muscle strength (3/5) in both lower limbs. The patient exhibited hyporeflexia in the knees and ankle. A magnetic resonance imaging (MRI) of the spine was performed, revealing a well-defined mass lesion located in the lumbar region, compressing the spinal cord from L2 to L5. The patient was counseled and prepared for surgical resection of the tumor. Histopathological findings revealed features of peripheral nerve sheath tumors and cellular schwannomas. The patient recovered well postoperatively. The surgeon operating should be mindful of the potential presence of a mobile schwannoma, even though it is rarely mentioned in the literature. Being aware of this possibility can help prevent unnecessary surgical dissection, which can lead to higher rates of complications and morbidity. Although it is plausible that this case could have involved a mobile schwannoma, there was not enough evidence to support it as we performed a laminectomy on multiple levels due to the tumor's size.
在过去十年中,成人良性脊柱肿瘤的增加一直是一个主要的担忧原因。这一令人担忧的趋势归因于许多因素,包括检测技术的改进、医疗服务可及性的提高以及人口老龄化。该研究主要关注神经鞘瘤,它是一种罕见的肿瘤,由施万细胞产生,施万细胞负责产生包围和保护神经的髓鞘。虽然大多数神经鞘瘤是良性的,但也有一些情况会转变为恶性肿瘤,可能导致严重的发病率和死亡率。我们报告一例68岁女性病例,她在过去几个月出现进行性背痛和双下肢无力。疼痛最初局限于下背部,但逐渐加剧并向下放射至腿部。患者报告行走困难,足部有刺痛和麻木感。她否认近期有任何外伤或重大病史。体格检查发现双下肢肌力减弱(3/5)。患者膝关节和踝关节反射减弱。对脊柱进行了磁共振成像(MRI)检查,发现一个边界清晰的肿块位于腰椎区域,从L2至L5压迫脊髓。患者接受了咨询并为肿瘤的手术切除做好了准备。组织病理学检查结果显示为周围神经鞘瘤和细胞性神经鞘瘤的特征。患者术后恢复良好。手术医生应注意移动性神经鞘瘤的潜在存在,尽管文献中很少提及。意识到这种可能性有助于防止不必要的手术解剖,这可能导致更高的并发症发生率和发病率。虽然该病例可能涉及移动性神经鞘瘤,但由于肿瘤大小我们进行了多个节段的椎板切除术,没有足够证据支持这一点。