Department of Orthopedic Surgery, Faculty of Medicine, Saga University, Saga, Japan.
Research Center for Arthroplasty, Faculty of Medicine, Saga University, Saga, Japan.
Bone Joint J. 2023 Jul 1;105-B(7):743-750. doi: 10.1302/0301-620X.105B7.BJJ-2023-0056.R1.
To clarify the mid-term results of transposition osteotomy of the acetabulum (TOA), a type of spherical periacetabular osteotomy, combined with structural allograft bone grafting for severe hip dysplasia.
We reviewed patients with severe hip dysplasia, defined as Severin IVb or V (lateral centre-edge angle (LCEA) < 0°), who underwent TOA with a structural bone allograft between 1998 and 2019. A medical chart review was conducted to extract demographic data, complications related to the osteotomy, and modified Harris Hip Score (mHHS). Radiological parameters of hip dysplasia were measured on pre- and postoperative radiographs. The cumulative probability of TOA failure (progression to Tönnis grade 3 or conversion to total hip arthroplasty) was estimated using the Kaplan-Meier product-limited method, and a multivariate Cox proportional hazard model was used to identify predictors for failure.
A total of 64 patients (76 hips) were included in this study. The median follow-up period was ten years (interquartile range (IQR) five to 14). The median mHHS improved from 67 (IQR 56 to 80) preoperatively to 96 (IQR 85 to 97) at the latest follow-up (p < 0.001). The radiological parameters improved postoperatively (p < 0.001), with the resulting parameters falling within the normal range in 42% to 95% of hips. The survival rate was 95% at ten years and 80% at 15 years. Preoperative Tönnis grade 2 was an independent risk factor for TOA failure.
Our findings suggest that TOA with structural bone allografting is a viable surgical option for correcting severely dysplastic acetabulum in adolescents and young adults without advanced osteoarthritis, with favourable mid-term outcomes.
阐明髋臼球形截骨术(TOA)的中期结果,该手术是一种球形髋臼周围截骨术,结合结构性同种异体骨移植治疗严重髋关节发育不良。
我们回顾了 1998 年至 2019 年间接受 TOA 加结构性骨移植物治疗的严重髋关节发育不良患者的病例。通过病历回顾提取人口统计学数据、与截骨术相关的并发症以及改良 Harris 髋关节评分(mHHS)。在术前和术后 X 线片上测量髋关节发育不良的放射学参数。使用 Kaplan-Meier 乘积限法估计 TOA 失败(进展为 Tönnis 3 级或转换为全髋关节置换术)的累积概率,并使用多变量 Cox 比例风险模型确定失败的预测因素。
本研究共纳入 64 例患者(76 髋)。中位随访时间为十年(四分位距(IQR)为 5 至 14)。mHHS 中位数从术前的 67(IQR 56 至 80)改善至末次随访时的 96(IQR 85 至 97)(p < 0.001)。术后放射学参数改善(p < 0.001),42%至 95%的髋关节参数恢复正常范围。10 年生存率为 95%,15 年生存率为 80%。术前 Tönnis 2 级是 TOA 失败的独立危险因素。
我们的研究结果表明,对于没有进展性骨关节炎的青少年和年轻成人,髋臼球形截骨术联合结构性骨移植是治疗严重髋臼发育不良的可行手术选择,中期结果良好。