Department of Psychiatry, Tokyo Medical University, Tokyo, Japan.
The Medical Foundation of Keishin-Kai, Kyouwa Hospital, Daisen, Akita, Japan.
J Nerv Ment Dis. 2023 Sep 1;211(9):704-710. doi: 10.1097/NMD.0000000000001688. Epub 2023 Jun 29.
The association between major depressive disorder (MDD) and personality traits has been extensively studied. However, differences in personality traits between patients with melancholic MDD (MEL) and nonmelancholic MDD (NMEL) remain unclear. In this study, we aimed to determine whether neuroticism, which has been associated with MDD, and the five affective temperament subtypes assessed by the Temperament Evaluation of Memphis, Pisa, Paris and San Diego-autoquestionnaire version (TEMPS-A) can be used to distinguish MEL and NMEL. A total of 106 patients with MDD (MEL, n = 52; NMEL, n = 54) and 212 age- and sex-matched healthy controls answered the Eysenck Personality Questionnaire-revised and the short version of TEMPS-A. In hierarchical logistic regression analysis, only depressive temperament scores were identified as a statistically significant feature distinguishing NMEL from MEL. Depressive temperament scores assessed by the short version of TEMPS-A were found to be significantly higher in NMEL patients than in MEL patients.
重度抑郁症（MDD）与人格特质之间的关联已得到广泛研究。然而，伴忧郁型 MDD（MEL）与非忧郁型 MDD（NMEL）患者之间的人格特质差异仍不清楚。在这项研究中，我们旨在确定神经质是否与 MDD 相关，以及通过 Memphis、Pisa、Paris 和 San Diego 自动问卷版（TEMPS-A）评估的五种情感气质亚型是否可用于区分 MEL 和 NMEL。共有 106 名 MDD 患者（MEL，n = 52；NMEL，n = 54）和 212 名年龄和性别匹配的健康对照者回答了艾森克人格问卷修订版和 TEMPS-A 短版。在分层逻辑回归分析中，只有抑郁气质评分被确定为区分 NMEL 与 MEL 的统计学显著特征。NMEL 患者的 TEMPS-A 短版评估的抑郁气质评分明显高于 MEL 患者。
