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简版TEMPS-A中文版的验证及其在情绪障碍患者中的应用

Validation of the Chinese Version of the Short TEMPS-A and its application in patients with mood disorders.

作者信息

Yuan Chengmei, Huang Jia, Gao Keming, Wu Zhiguo, Chen Jun, Wang Yong, Hong Wu, Yi Zhenghui, Hu Yingyan, Cao Lan, Li Zezhi, Akiskal Kareen K, Akiskal Hagop S, Wang Biao, Fang Yiru

机构信息

First Department of General Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China.

Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 600 Wan Ping Nan Road, Shanghai 200030, China.

出版信息

J Affect Disord. 2015 Jan 1;170:178-84. doi: 10.1016/j.jad.2014.08.041. Epub 2014 Sep 3.

DOI:10.1016/j.jad.2014.08.041
PMID:25243747
Abstract

BACKGROUND

The short version of Temperament Evaluation of the Memphis, Pisa, Paris, and San Diego-Auto-questionnaire (TEMPS-A) is a useful instrument to measure affective temperaments. Aims of the present study are to validate the Chinese Version of the Short TEMPS-A, and to explore whether it could be useful to distinguish patients with mood disorders from healthy controls or differentiate patients with bipolar disorder (BPD) from those with major depressive disorder (MDD) in Chinese population.

METHODS

A sample of 715 participants, including 387 patients with MDD, 143 with BPD and 185 healthy controls, was recruited. All participants completed The Chinese Version of the Short TEMPS-A. Standard psychometric tests of reliability and validation were performed. ANOVA, non-parameter test and Multiple Logistic Regression were used to test the association between TEMPS-A scores and mood disorders.

RESULTS

The originally proposed five factors of the Chinese Version of the Short TEMPS-A were upheld. The Chronbach-Alpha coefficients of it varied from 0.70 to 0.89 and test-retest Spearman׳s Correlation Coefficients varied from 0.52 to 0.85. Significant differences were found across the three groups on all five TEMPS-A subscales (P<0.001). Multiple Logistic Regression showed that hyperthymic temperament distinguished patients with BPD from those with MDD (OR 1.28, 95% CI 1.14-1.45, P<0.001) after controlling for age, gender and the severity of depression.

LIMITATIONS

The cross-sectional self-report design, unbalanced demographic characteristics and undifferentiated subtypes of bipolar disorders might limit the generalizability of the results.

CONCLUSION

The Chinese Version of the Short TEMPS-A shows good reliability and validity. It might be used as a screening tool in the general population to identify the vulnerability for developing a mood disorder and the potential risk for bipolar disorder among those who only have depressive symptoms.

摘要

背景

孟菲斯、比萨、巴黎和圣地亚哥气质评估简版自陈问卷(TEMPS-A)是一种用于测量情感气质的有效工具。本研究的目的是验证中文版TEMPS-A简版,并探讨其在中国人群中区分心境障碍患者与健康对照,或区分双相情感障碍(BPD)患者与重度抑郁症(MDD)患者是否有用。

方法

招募了715名参与者,包括387例MDD患者、143例BPD患者和185名健康对照。所有参与者均完成中文版TEMPS-A简版。进行了标准的信效度心理测量测试。采用方差分析、非参数检验和多元逻辑回归来检验TEMPS-A得分与心境障碍之间的关联。

结果

中文版TEMPS-A简版最初提出的五个因子得以维持。其Chronbach-Alpha系数在0.70至0.89之间,重测斯皮尔曼相关系数在0.52至0.85之间。在TEMPS-A的所有五个分量表上,三组之间均存在显著差异(P<0.001)。多元逻辑回归显示,在控制年龄、性别和抑郁严重程度后,环性气质可区分BPD患者与MDD患者(OR 1.28,95%CI 1.14 - 1.45,P<0.001)。

局限性

横断面自陈设计、不均衡的人口统计学特征以及双相情感障碍未分化的亚型可能会限制结果的普遍性。

结论

中文版TEMPS-A简版显示出良好的信效度。它可作为一般人群的筛查工具,以识别患心境障碍的易感性以及仅具有抑郁症状者中双相情感障碍的潜在风险。

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