Suman Satyam, Biswas Anupam, Kohaf Neveen, Singh Chhaya, Johns Riya, Jakkula Pravalika, Hastings Natasha
Department of Clinical Pharmacy and Clinical Pharmacology, Fortis Hospital, Noida, INDIA.
Department of Endocrinology and Diabetology, Fortis Hospital, Noida, INDIA.
Curr Probl Cardiol. 2023 Nov;48(11):101923. doi: 10.1016/j.cpcardiol.2023.101923. Epub 2023 Jul 1.
Diabetes and heart disease are 2 prevalent and interconnected conditions with a significant global burden. Understanding the relationship between diabetes and heart disease is crucial for effective management and prevention strategies. This article provides an overview of the 2 conditions, highlighting their types, risk factors, and global prevalence. Recent research findings establish a strong correlation between diabetes and various aspects of cardiovascular health, including coronary artery disease, heart failure, and stroke. Mechanisms such as insulin resistance, inflammation, and oxidative stress contribute to the interplay between diabetes and heart disease. The implications for clinical practice underscore the importance of early detection, risk assessment, and comprehensive management of both conditions. Lifestyle modifications, such as diet, exercise, and weight management, are essential interventions. Pharmacological interventions, including antidiabetic drugs and cardiovascular medications, play a crucial role in treatment. Managing diabetes and heart disease simultaneously poses challenges that require interdisciplinary collaboration among endocrinologists, cardiologists, and primary care physicians. Ongoing research explores personalized medicine and targeted therapies as potential future directions. Continued research and awareness are paramount to mitigate the impact of the diabetes-heart disease connection and improve patient outcomes.
糖尿病和心脏病是两种普遍且相互关联的疾病,在全球造成了重大负担。了解糖尿病与心脏病之间的关系对于有效的管理和预防策略至关重要。本文概述了这两种疾病,重点介绍了它们的类型、风险因素和全球患病率。最近的研究结果表明,糖尿病与心血管健康的各个方面,包括冠状动脉疾病、心力衰竭和中风,之间存在着密切的关联。胰岛素抵抗、炎症和氧化应激等机制促成了糖尿病与心脏病之间的相互作用。对临床实践的影响强调了早期检测、风险评估以及对这两种疾病进行综合管理的重要性。生活方式的改变,如饮食、运动和体重管理,是必不可少的干预措施。药物干预,包括抗糖尿病药物和心血管药物,在治疗中起着关键作用。同时管理糖尿病和心脏病带来了挑战,需要内分泌学家、心脏病学家和初级保健医生之间进行跨学科合作。正在进行的研究探索个性化医疗和靶向治疗作为潜在的未来方向。持续的研究和认识对于减轻糖尿病与心脏病关联的影响以及改善患者预后至关重要。