Zand Ashkan, Ibrahim Karim, Patham Bhargavi
HOUSTON METHODIST HOSPITAL, HOUSTON, TEXAS.
Methodist Debakey Cardiovasc J. 2018 Oct-Dec;14(4):289-297. doi: 10.14797/mdcj-14-4-289.
A clear link between cardiovascular disease and prediabetes has emerged over the past few years. Recent studies have shown that patients with prediabetes can suffer from coronary artery disease and diastolic heart failure even before progressing to overt diabetes. With this knowledge, physicians must identify prediabetes and take appropriate measures to optimize glycemic control. The pathophysiological defect seen in prediabetes can be managed with lifestyle modifications; thus, it is essential that physicians have a clear understanding of the current recommendations regarding diet and exercise. This review outlines the complications associated with prediabetes, presents an overview of the available pharmacological and surgical therapies that are effective in treating it, and provides a stepwise, multipronged approach for management.
在过去几年中,心血管疾病与糖尿病前期之间已出现明确的联系。最近的研究表明,糖尿病前期患者甚至在发展为显性糖尿病之前就可能患有冠状动脉疾病和舒张性心力衰竭。基于这一认识,医生必须识别糖尿病前期,并采取适当措施优化血糖控制。糖尿病前期出现的病理生理缺陷可通过生活方式改变来控制;因此,医生清楚了解当前关于饮食和运动的建议至关重要。本综述概述了与糖尿病前期相关的并发症,介绍了有效治疗糖尿病前期的现有药物和手术治疗方法,并提供了一种逐步的、多方面的管理方法。