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音乐与遗传学。

Music and Genetics.

机构信息

Department of Neuroscience, Karolinska Institutet, Sweden; Department of Psychiatry, Amsterdam UMC, University of Amsterdam, Netherlands; Department of Cognitive Neuropsychology, Max Planck Institute for Empirical Aesthetics, Frankfurt am Main, Germany.

Department of Neuroscience, Karolinska Institutet, Sweden; Department of Cognitive Neuropsychology, Max Planck Institute for Empirical Aesthetics, Frankfurt am Main, Germany.

出版信息

Neurosci Biobehav Rev. 2023 Sep;152:105302. doi: 10.1016/j.neubiorev.2023.105302. Epub 2023 Jul 1.

Abstract

The first part of this review provides a brief historical background of behavior genetic research and how twin and genotype data can be utilized to study genetic influences on individual differences in human behavior. We then review the field of music genetics, from its emergence to large scale twin studies and the recent, first molecular genetic studies of music-related traits. In the second part of the review, we discuss the wider utility of twin and genotype data beyond estimating heritability and gene-finding. We present four examples of music studies that utilized genetically informative samples to analyze causality and gene-environmental interplay for music skills. Overall, research in the field of music genetics has gained much momentum over the last decade and its findings highlight the importance of studying both environmental and genetic factors and particularly their interplay, paving the way for exciting and fruitful times to come.

摘要

这篇综述的第一部分简要介绍了行为遗传学研究的历史背景,以及如何利用双胞胎和基因型数据来研究遗传对人类行为个体差异的影响。然后,我们回顾了音乐遗传学领域,从其出现到大规模双胞胎研究,以及最近与音乐相关特征的首个分子遗传学研究。在综述的第二部分,我们讨论了除了估计遗传率和发现基因之外,双胞胎和基因型数据的更广泛应用。我们提出了四个利用遗传信息样本分析音乐技能的因果关系和基因-环境相互作用的音乐研究示例。总体而言,过去十年中,音乐遗传学领域的研究取得了很大进展,其研究结果强调了研究环境和遗传因素及其相互作用的重要性,为未来令人兴奋和富有成果的时代铺平了道路。

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