Bignardi Giacomo, Wesseldijk Laura W, Mas-Herrero Ernest, Zatorre Robert J, Ullén Fredrik, Fisher Simon E, Mosing Miriam A
Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands.
Max Planck School of Cognition, Leipzig, Germany.
Nat Commun. 2025 Mar 25;16(1):2904. doi: 10.1038/s41467-025-58123-8.
Humans engage with music for various reasons that range from emotional regulation and relaxation to social bonding. While there are large inter-individual differences in how much humans enjoy music, little is known about the origins of those differences. Here, we disentangle the genetic factors underlying such variation. We collect data on several facets of music reward sensitivity, as measured by the Barcelona Music Reward Questionnaire, plus music perceptual abilities and general reward sensitivity from a large sample of Swedish twins (N = 9169; 2305 complete pairs). We estimate that genetic effects contribute up to 54% of the variability in music reward sensitivity, with 70% of these effects being independent of music perceptual abilities and general reward sensitivity. Furthermore, multivariate analyses show that genetic and environmental influences on the different facets of music reward sensitivity are partly distinct, uncovering distinct pathways to music enjoyment and different patterns of genetic associations with objectively assessed music perceptual abilities. These results paint a complex picture in which partially distinct sources of variation contribute to different aspects of musical enjoyment.
人类因各种原因接触音乐，这些原因从情绪调节、放松到社会联结不等。虽然人类对音乐的喜爱程度存在很大的个体差异，但对于这些差异的起源却知之甚少。在这里，我们剖析了造成这种差异的遗传因素。我们收集了关于音乐奖励敏感性几个方面的数据，这些数据通过巴塞罗那音乐奖励问卷来衡量，此外还收集了来自大量瑞典双胞胎样本（N = 9169；2305对完整双胞胎）的音乐感知能力和一般奖励敏感性数据。我们估计，遗传效应在音乐奖励敏感性的变异性中所占比例高达54%，其中70%的效应独立于音乐感知能力和一般奖励敏感性。此外，多变量分析表明，遗传和环境对音乐奖励敏感性不同方面的影响部分是不同的，揭示了通往音乐享受的不同途径以及与客观评估的音乐感知能力的不同遗传关联模式。这些结果描绘了一幅复杂的图景，其中部分不同的变异来源促成了音乐享受的不同方面。
