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短种植体与常规种植体在后萎缩性下颌骨骨增量后的比较:成功结局的伞式综述和荟萃分析。

Short implants compared to regular dental implants after bone augmentation in the atrophic posterior mandible: umbrella review and meta-analysis of success outcomes.

机构信息

Faculty of Dentistry, Center for Epidemiology and Surveillance of Oral Diseases, University of Chile, Santiago, Chile.

Faculty of Dentistry, University of Chile, Santiago, Chile.

出版信息

Int J Implant Dent. 2023 Jul 4;9(1):18. doi: 10.1186/s40729-023-00476-0.

Abstract

PURPOSE

To assess the body of evidence of short versus regular implants after bone augmentation (BA) in the atrophic posterior mandible in the context of implant treatment success outcomes.

METHODS

Seven databases, two registries, and reference lists were searched for systematic reviews and meta-analysis (SR/MA), randomized controlled trials (RCTs) and longitudinal studies published in English, Spanish or German since 2012. Confidence in the SR/MA methodology was evaluated using AMSTAR-2 and the risk of bias of primary studies using Cochrane's RoB 2.0 and ROBINS-I. A random-effects meta-analysis and a meta-regression were performed for continuous and dichotomous outcomes. GRADE approach was used to assess the certainty of the evidence.

RESULTS

Eighteen SRs/MAs, most of them "critically low" and "low" confidence with substantial overlap, included 14 relevant RCTs with a high risk of bias. A cohort study with moderate risk of bias was added. Quantitative synthesis of 595 implants and 281 hemiarches/patients indicates that the use of short implants (< 10 mm) compared to regular implants and BA may reduce implant failure at 1-year follow-up, and marginal bone loss (MBL) at 3-, 5-, and 8-year follow-up; is likely to reduce the risk of biological complications at 1-, 3-, 5-, and 8-year follow-up; and may be the patient's preferred alternative. There is a correlation between bone height, MBL and biological complications.

CONCLUSIONS

The available evidence partially suggests that the use of short implants could decrease implant failure, MBL, and biological complications, and increase patient satisfaction. However, given the need for further RCTs and real-world evidence to fully evaluate short- and long-term outcomes, it would be prudent for clinicians to carefully consider the individual needs and circumstances of the patients before deciding whether to use short implants. Trial registration PROSPERO CRD42022333526.

摘要

目的

评估在后萎缩下颌骨骨增量(BA)背景下,短种植体与常规种植体在种植体治疗成功结局方面的证据体。

方法

检索了 7 个数据库、2 个登记处和参考文献,以寻找自 2012 年以来发表的英文、西班牙文或德文的系统评价和荟萃分析(SR/MA)、随机对照试验(RCT)和纵向研究。使用 AMSTAR-2 评估 SR/MA 方法学的可信度,使用 Cochrane 的 RoB 2.0 和 ROBINS-I 评估主要研究的偏倚风险。对连续和二分类结局进行随机效应荟萃分析和荟萃回归。使用 GRADE 方法评估证据的确定性。

结果

18 项 SR/MA 中,大多数可信度为“极低”和“低”,存在大量重叠,包括 14 项具有高偏倚风险的相关 RCT。增加了一项偏倚风险为中度的队列研究。对 595 枚种植体和 281 半颌/患者的定量综合分析表明,与常规种植体和 BA 相比,使用短种植体(<10mm)可能会降低 1 年随访时的种植体失败率,以及 3 年、5 年和 8 年随访时的边缘骨丧失(MBL);可能降低 1 年、3 年、5 年和 8 年随访时的生物并发症风险;可能是患者更倾向的选择。骨高度、MBL 和生物并发症之间存在相关性。

结论

现有证据部分表明,使用短种植体可能会降低种植体失败、MBL 和生物并发症的发生率,并提高患者满意度。然而,鉴于需要进一步的 RCT 和真实世界证据来全面评估短期和长期结局,临床医生在决定是否使用短种植体之前,应仔细考虑患者的个体需求和情况,这是谨慎的做法。试验注册 PROSPERO CRD42022333526。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a557/10317914/35174886440e/40729_2023_476_Fig1_HTML.jpg

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