Esposito Marco, Pistilli Roberto, Barausse Carlo, Felice Pietro
Eur J Oral Implantol. 2014 Winter;7(4):383-95.
To evaluate whether 5-mm short dental implants could be an alternative to augmentation with anorganic bovine bone and placement of at least 10-mm long implants in posterior atrophic jaws.
Fifteen patients with bilateral atrophic mandibles (5 mm to 7 mm bone height above the mandibular canal) and 15 patients with bilateral atrophic maxillae (4 mm to 6 mm bone height below the maxillary sinus), and bone thickness of at least 8 mm, were randomised according to a split-mouth design to receive one to three 5-mm short implants or at least 10-mm long implants in augmented bone. Mandibles were vertically augmented with interpositional bone blocks and maxillary sinuses with particulated bone via a lateral window. Implants were placed after 4 months, submerged and loaded, after another 4 months, with provisional prostheses. Four months later, definitive provisionally cemented prostheses were delivered. Outcome measures were: prosthesis and implant failures; any complication and peri-implant marginal bone level changes.
In five augmented mandibles, the planned 10-mm long implants could not be placed and shorter implants (7 mm and 8.5 mm) had to be used instead. Three years after loading, two patients, one treated in the mandible and one in the maxilla, dropped out. Three prostheses (1 mandibular and 2 maxillary) failed in the short implant group versus none in the long implant group. In mandibles, one long implant failed versus two short implants in 1 patient. In maxillae, one long implant failed versus three short implants in 2 patients. There were no statistically significant differences in the failures. Eight patients had 13 complications at short implants (1 patient accounted for 6 complications) and 11 patients had 13 complications at long implants. There were no statistically significant differences in complications (P = 0.63, difference = 0.10, 95% CI from -0.22 to 0.42). Three years after loading, patients with mandibular implants lost on average 1.44 mm at short implants and 1.63 mm at long implants of peri-implant marginal bone. This difference was not statistically significant (difference = 0.24 mm; 95% CI -0.01, 0.49 P = 0.059). In maxillae, patients lost on average 1.02 mm at short implants and 1.54 mm at long implants. This difference was statistically significant (difference = 0.41 mm; 95% CI 0.21, 0.60, P = 0.001).
Three years after loading, 5-mm short implants achieved similar results as longer implants in augmented bone. Short implants might be a preferable choice to vertical bone augmentation, especially in mandibles, since the treatment is faster and cheaper, however there are still insufficient data on the long-term prognosis of short implants.
评估5毫米短种植体是否可替代使用无机牛骨进行骨增量并植入至少10毫米长种植体的方法,用于治疗后牙区萎缩性颌骨。
选取15例双侧下颌骨萎缩患者(下颌管上方骨高度为5毫米至7毫米)和15例双侧上颌骨萎缩患者(上颌窦下方骨高度为4毫米至6毫米),且骨厚度至少为8毫米,根据分口设计将患者随机分组,分别在骨增量后植入1至3枚5毫米短种植体或至少10毫米长种植体。下颌骨采用植入骨块进行垂直骨增量,上颌窦通过外侧开窗植入颗粒状骨进行骨增量。4个月后植入种植体,采用潜入式种植,再经过4个月,安装临时义齿并加载。4个月后,交付最终的临时粘结义齿。观察指标包括:义齿和种植体失败情况;任何并发症以及种植体周围边缘骨水平变化。
在5例骨增量后的下颌骨中,无法植入计划中的10毫米长种植体,不得不改用较短的种植体(7毫米和8.5毫米)。加载3年后,2例患者退出研究,其中1例下颌骨患者,1例上颌骨患者。短种植体组有3例义齿失败(1例下颌,2例上颌),而长种植体组无义齿失败。在下颌骨中,1例长种植体失败,1例患者的2枚短种植体失败。在上颌骨中,1例长种植体失败,2例患者的3枚短种植体失败。失败情况无统计学显著差异。8例患者的短种植体出现13例并发症(1例患者出现6例并发症),11例患者的长种植体出现13例并发症。并发症无统计学显著差异(P = 0.63,差值 = 0.10,95%可信区间为 -0.22至0.42)。加载3年后,下颌种植体患者短种植体周围边缘骨平均吸收1.44毫米,长种植体周围边缘骨平均吸收1.63毫米。这种差异无统计学显著意义(差值 = 0.24毫米;95%可信区间 -0.01,0.49,P = 0.059)。在上颌骨中,短种植体患者平均吸收1.02毫米,长种植体患者平均吸收1.54毫米。这种差异具有统计学显著意义(差值 = 0.41毫米;95%可信区间0.21,0.60,P = 0.001)。
加载3年后,5毫米短种植体在骨增量后的效果与较长种植体相似。短种植体可能是垂直骨增量的更优选择,尤其是在下颌骨,因为治疗更快且成本更低,然而关于短种植体长期预后的数据仍然不足。