Division of Thoracic Surgery and Lung Transplant, AOU Policlinico Umberto I, University of Rome Sapienza, Viale del Policlinico 155, 00161, Rome, Italy.
Department of Radiological, Oncological and Pathological Sciences, University of Rome Sapienza, Rome, Italy.
J Cardiothorac Surg. 2023 Jul 3;18(1):205. doi: 10.1186/s13019-023-02315-0.
Xanthomas are well-circumscribed benign proliferative lesions seen mainly in soft tissues. Usually, they are found in hyperlipidemia and familial hyperlipoproteinemia. Histologically, are characterized by macrophage-like mononuclear cells, multinucleated giant cells and abundant foam cells. The bone involvement, however, is notoriously rare and rib localization is extremely rare.
A 55-year-old man performed a chest X-ray and a subsequent chest Computed Tomography scan showing a rib lesion that was surgically removed and a diagnosis of rib xanthoma was made. The patient presented an unknown condition of hyperlipidemia.
Rib xanthoma can be discovered accidentally and can be helpful in identifying an unrecognized condition of hyperlipidemia.
黄瘤是主要见于软组织的界限清楚的良性增生性病变。通常，它们发生于高脂血症和家族性高脂蛋白血症。组织学上，其特征是巨噬细胞样单核细胞、多核巨细胞和丰富的泡沫细胞。然而，骨骼受累是罕见的，肋骨定位更是极其罕见。
一名 55 岁男性进行了胸部 X 射线检查和随后的胸部计算机断层扫描，显示肋骨病变，病变被手术切除，诊断为肋骨黄瘤。患者患有不明原因的高脂血症。
肋骨黄瘤可以偶然发现，并有助于识别未被认识的高脂血症。
