Guerrouj Hasnae, Mouaden Ayat, Benrais Nouzha
Nuclear Medicine Department, University of Mohammed V-Souissi, Rabat, Morocco.
Case Rep Endocrinol. 2012;2012:986952. doi: 10.1155/2012/986952. Epub 2012 Apr 8.
Bone xanthoma is a rare disease due to the presence of cholesterol deposits in the bone. We report a case of a 56-year-old patient who was hospitalized in orthopedic department for fracture on the left humerus. Histological examination of bone biopsy performed at this site has objectified cholesterol deposits. Laboratory tests showed hypercholesterolemia with hypertriglyceridemia. The diagnosis of bone xanthoma was selected. The fracture was treated surgically. An initial bone scan revealed bone lesions localized especially at the humerus and femur. The patient was put under fenofibrate and statins. The evolution was marked by gradual regression of lesions in bone scans of control.
骨黄瘤是一种罕见疾病，因骨内存在胆固醇沉积所致。我们报告一例56岁患者，因左肱骨骨折入住骨科。对该部位进行的骨活检组织学检查证实有胆固醇沉积。实验室检查显示高胆固醇血症伴高甘油三酯血症。确诊为骨黄瘤。骨折接受了手术治疗。最初的骨扫描显示骨病变主要位于肱骨和股骨。患者接受非诺贝特和他汀类药物治疗。病情进展表现为对照骨扫描中病变逐渐消退。
