Baek Hee Sun, Cho Min Hyun
Department of Pediatrics, Yeungnam University, College of Medicine, Daegu, Korea.
Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, Korea.
Clin Exp Pediatr. 2023 Oct;66(10):424-431. doi: 10.3345/cep.2023.00738. Epub 2023 Jun 28.
Coronavirus disease 2019 (COVID-19) has spread considerably across the globe, affecting numerous children and adolescents besides adults. Despite its relatively lower incidence rates in children and adolescents than in adults, some infected children and adolescents exhibit a severe postinflammatory response known as multisystem inflammatory syndrome in children, followed by acute kidney injury, a common complication. Meanwhile, few reports have been available regarding kidney complications such as idiopathic nephrotic syndrome and other glomerulopathies associated with COVID-19 infection and vaccination in children and adolescents. However, the morbidity and mortality of these complications are not exceptionally high; more importantly, causality has yet to be clearly established. Finally, vaccine hesitancy in these age groups should be addressed, considering the strong evidence of COVID-19 vaccine safety and efficacy.
2019冠状病毒病（COVID-19）已在全球范围内广泛传播，除成年人外，还影响了众多儿童和青少年。尽管儿童和青少年中的发病率相对低于成年人，但一些受感染的儿童和青少年会出现一种称为儿童多系统炎症综合征的严重炎症后反应，随后会出现急性肾损伤这一常见并发症。与此同时，关于儿童和青少年中与COVID-19感染及疫苗接种相关的特发性肾病综合征和其他肾小球病等肾脏并发症的报道较少。然而，这些并发症的发病率和死亡率并非特别高；更重要的是，因果关系尚未明确确立。最后，鉴于有充分证据证明COVID-19疫苗的安全性和有效性，应解决这些年龄组中对疫苗的犹豫问题。
