Tamiya K, Higashidate M, Kikkawa S
Am J Physiol. 1986 Aug;251(2 Pt 2):H236-41. doi: 10.1152/ajpheart.1986.251.2.H236.
A new measuring system that permits real-time registration of the tricuspid valve annular area (TVA) using lock-in amplifier is devised and applied in open-chest anesthetized dogs. The tricuspid valve annulus was stitched with a fine, pliable, metal thread made of 10 30-micron urethane resin-coated copper wires during inflow occlusion. Both ends of the thread were guided out from the right atrium through a single pinhole in the right atrial wall. The signal intensity induced in the sense loop is linearly related to the area encircled by the thread, i.e., the area of the tricuspid annulus. During control state, TVA varied by an average of 24.5% (3.8-46.5%) of its maximum. Presystolic peak and valley of TVA due to atrial contraction and a decrease in TVA during ventricular ejection were generally observed. An increase in TVA during the initial portion of isovolumic contraction phase was prominent in dogs with filariasis, whereas in the other dogs it was not.
设计了一种新的测量系统，该系统使用锁相放大器允许实时记录三尖瓣环面积（TVA），并应用于开胸麻醉犬。在流入道闭塞期间，用由10根30微米聚氨酯树脂涂层铜线制成的细的、柔韧的金属线缝合三尖瓣环。金属线的两端通过右心房壁上的单个针孔从右心房引出。感应回路中感应的信号强度与金属线环绕的面积，即三尖瓣环的面积呈线性相关。在对照状态下，TVA平均变化为其最大值的24.5%（3.8 - 46.5%）。通常观察到由于心房收缩导致的TVA的收缩前期峰值和谷值以及心室射血期间TVA的减小。在患有丝虫病的犬中，等容收缩期初始部分TVA的增加很明显，而在其他犬中则不明显。
