Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California.
Cancer Epidemiol Biomarkers Prev. 2023 Jul 5;32(7):876-878. doi: 10.1158/1055-9965.EPI-23-0326.
Metrics of cancer burden stratified by race can inform tailored prevention strategies. Examining how these metrics, such as incidence, vary by immigration status can provide insight into the drivers of differential cancer risk by race. The conduct of such analyses in Canada has historically been hindered by a lack of sociodemographic data in routine health data sources, including cancer registries. In their recent study, Malagón and colleagues overcome this challenge by using National Cancer Registry data linked to self-reported race and place of birth from the Canadian census. The study provides estimates of cancer incidence for 19 cancer sites across more than 10 racial groups. Compared with the total population, they found that cancer risk tended to be lower among persons belonging to non-White, non-Indigenous racial groups. Exceptions were stomach, liver, and thyroid cancers where incidence rates were higher in minority groups than in the White population. For some cancers and racial groups, incidence was lower irrespective of immigration status, suggesting the healthy immigrant effect may be sustained across generations or that other factors are also at play. The results highlight potential areas for deeper inquiry and underscore the value of sociodemographic data for disease surveillance. See related article by Malagón et al., p. 906.
癌症负担指标按种族分层，可以为有针对性的预防策略提供信息。研究这些指标（如发病率）如何随移民身份而变化，可以深入了解导致不同种族癌症风险差异的因素。在加拿大，由于癌症登记处等常规卫生数据来源缺乏社会人口数据，历史上一直难以进行此类分析。在最近的研究中，Malagón 及其同事通过使用与加拿大人口普查报告的种族和出生地相关的国家癌症登记处数据，克服了这一挑战。该研究提供了 19 个癌症部位在 10 多个种族群体中的癌症发病率估计。与总人口相比，他们发现属于非白人和非原住民种族群体的人的癌症风险往往较低。但也有例外，如胃癌、肝癌和甲状腺癌，少数族裔的发病率高于白人。对于某些癌症和种族群体，无论移民身份如何，发病率都较低，这表明健康移民效应可能在几代人中持续存在，或者还有其他因素在起作用。研究结果突出了深入研究的潜在领域，并强调了社会人口数据对疾病监测的价值。有关 Malagón 等人的相关文章，请参见第 906 页。
