Woods Ryan R, Kliewer Erich V, McGrail Kimberlyn M, Spinelli John J
Faculty of Health Sciences, Simon Fraser University, Burnaby, Canada.
Cancer Control Research, BC Cancer, 2nd Floor, 675 W 10th Ave, V5Z 1L3, Vancouver, BC, Canada.
J Immigr Minor Health. 2023 Feb;25(1):232-236. doi: 10.1007/s10903-022-01378-w. Epub 2022 Jun 29.
Breast cancer screening utilization varies across immigrant and non-immigrant populations. Recent studies have also suggested that some immigrant populations in Canada present with a higher frequency of later-stage breast cancer compared to non-immigrants. Our study aimed to augment prior research by presenting breast cancer stage distributions and stage-specific breast cancer incidence rates for immigrant and non-immigrants in British Columbia, Canada.
We utilized a population-based cohort of more than 1.3 million women built from linked administrative health and immigration data sets. Age-standardized incidence rate ratios were generated to compare immigrant and non-immigrant groups. Poisson regression was used to assess the relative frequency of later stage diagnosis among immigrant groups compared to non-immigrants.
Indian and Chinese immigrants both showed significantly lower stage I and stage II-IV incidence rates compared to non-immigrants. However, Indian immigrants showed a higher frequency of later stage tumours at diagnosis compared to non-immigrants, while in contrast Chinese immigrants showed a lower frequency of later stage tumours. Filipino immigrants showed similar stage-specific rates and stage at diagnosis compared to non-immigrants.
Our findings highlight a need for continued surveillance of cancer among immigrant and non-immigrant populations and inquiry into reasons for differences in stage at diagnosis across groups.
乳腺癌筛查的利用率在移民和非移民人群中存在差异。最近的研究还表明，与非移民相比，加拿大的一些移民人群晚期乳腺癌的发病率更高。我们的研究旨在通过呈现加拿大不列颠哥伦比亚省移民和非移民的乳腺癌分期分布以及特定分期的乳腺癌发病率，来补充先前的研究。
我们利用了一个基于人群的队列，该队列由超过130万女性组成，数据来自于关联的行政健康和移民数据集。生成年龄标准化发病率比以比较移民和非移民群体。使用泊松回归来评估移民群体与非移民相比晚期诊断的相对频率。
与非移民相比，印度和中国移民的I期和II-IV期发病率均显著较低。然而，与非移民相比，印度移民在诊断时晚期肿瘤的频率较高，而中国移民则相反，晚期肿瘤的频率较低。菲律宾移民与非移民相比，在诊断时的特定分期率和分期相似。
我们的研究结果强调了对移民和非移民人群的癌症持续监测的必要性，并探究各群体诊断分期差异的原因。
