Srinivas Dasari, Mounika Kurella, Satyanarayana Gedu
Department of Chemistry, Indian Institute of Technology (IIT), Hyderabad, Kandi, Sangareddy - 502284, India.
Chem Commun (Camb). 2023 Jul 20;59(59):9106-9109. doi: 10.1039/d3cc02260a.
Herein, we report the -C-H olefination of arylmethanesulfonates aided by a potentially versatile aliphatic nitrile-directing group under microwave irradiation conditions with fair to very good yields and good to outstanding regioselectivities. Significantly, the protocol showed broad substrate scope including olefin-derived drugs and cyclic olefins. Remarkably, a dual -C-H bond was amenable to generating the bis-olefination products.
