Cook P T, Lambert T F
Anaesth Intensive Care. 1986 May;14(2):148-51. doi: 10.1177/0310057X8601400209.
Sixty women having laparoscopic sterilisation performed under general anaesthesia were randomly allocated to one of two groups. Intraoperatively, one group had bupivacaine applied topically to the fallopian tubes and injected into the skin wounds, while the other group received no local anaesthetic. A double-blind investigation utilising a visual analogue scale failed to demonstrate a statistically significant difference in postoperative pain between the two groups. In both groups there was a significant reduction in mean pain scores between 1/2 and 7 hours, but there was no further reduction between 7 hours and 17 hours. At 7 hours, only 10% of patients scored their pain as 3 or greater (out of a possible 10). It is concluded that the use of bupivacaine as described is not a useful adjuvant to general anaesthesia and that the low incidence of even moderate pain at 7 hours confirms the view that these patients are suitable for management in the day-stay unit.
60名接受全身麻醉下腹腔镜绝育术的女性被随机分为两组。术中，一组将布比卡因局部应用于输卵管并注射到皮肤伤口，而另一组未接受局部麻醉。使用视觉模拟量表进行的双盲调查未能显示两组术后疼痛存在统计学上的显著差异。两组患者在术后1.5小时至7小时之间平均疼痛评分均显著降低，但在7小时至17小时之间没有进一步降低。在7小时时，只有10%的患者将疼痛评分为3分或更高（满分10分）。结论是，所述布比卡因的使用并非全身麻醉的有效辅助手段，并且7小时时即使中度疼痛的发生率较低证实了这些患者适合在日间病房进行管理的观点。
