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人工授精中的流产率与精液特征:对1345例妊娠的研究

Abortion rate in A.I.D. and semen characteristics: a study of 1345 pregnancies.

作者信息

Schwartz D, Mayaux M J, Guihard-Moscato M L, Czyglik F, David G

出版信息

Andrologia. 1986 May-Jun;18(3):292-8. doi: 10.1111/j.1439-0272.1986.tb01779.x.

Abstract

A study undertaken on 1345 pregnancies resulting from artificial insemination with donor showed an 18% risk of abortion. This figure is the same as that admitted for natural reproduction. It does not depend on any of the classically studied semen characteristics and in particular remains invariant whatever the postthaw motility, the factor most strongly linked to conception rate. Two results, well known from the literature, i.e. the increased abortion rate mentioned in natural reproduction when the sperm is of poor quality and the high incidence of repeated abortions when sperm quality is particularly good are discussed. The first of these results cannot be considered as being established in a statistically significant way. The second may result from different sources of bias, some of which are identified. In essence a high frequency of abortions signifies simply a high frequency of pregnancies, it is therefore not surprising that the semen is in this case particularly good.

摘要

一项针对1345例供体人工授精妊娠的研究显示,流产风险为18%。这一数字与自然生殖的公认数字相同。它不取决于任何经典研究的精液特征,特别是无论解冻后活力如何,该数字都保持不变,解冻后活力是与受孕率联系最紧密的因素。文献中熟知的两个结果,即在自然生殖中精子质量差时流产率增加,以及精子质量特别好时反复流产的高发生率,在此进行了讨论。第一个结果在统计学上不能被视为已确立。第二个结果可能源于不同的偏差来源,其中一些偏差已被识别。本质上,高流产率仅仅意味着高妊娠率,因此在这种情况下精液特别好也就不足为奇了。

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