Bryant Richard A, McFarlane Alexander C, Silove Derrick, O'Donnell Meaghan L, Forbes David, Creamer Mark
School of Psychology, University of New South Wales (Bryant); Brain Dynamics Centre, Westmead Millennium Institute (Bryant); Centre for Military and Veteran Health, University of Adelaide (McFarlane); School of Psychiatry, University of New South Wales (Silove); and Phoenix Australia, Centre for Posttraumatic Mental Health, Department of Psychiatry, University of Melbourne (O'Donnell, Forbes, Creamer).
Focus (Am Psychiatr Publ). 2023 Jul;21(3):290-295. doi: 10.1176/appi.focus.23021016. Epub 2023 Jun 28.
This study investigated whether impairment persists after posttraumatic stress disorder (PTSD) has resolved. Traumatically injured patients ( = 1,035) were assessed during hospital admission and at 3 (85%) and 12 months (73%). Quality of life prior to traumatic injury was measured with the World Health Organization Quality of Life-BREF during hospitalization and at each subsequent assessment. PTSD was assessed using the Clinician-Administered PTSD Scale at 3 and 12 months. After controlling for preinjury functioning, current pain, and comorbid depression, patients whose PTSD symptoms had resolved by 12 months were more likely to have poorer quality of life in psychological (OR = 3.51), physical (OR = 10.17), social (OR = 4.54), and environmental (OR = 8.83) domains than those who never developed PTSD. These data provide initial evidence that PTSD can result in lingering effects on functional capacity even after remission of symptoms. Reprinted from , with permission from Sage. Copyright © 2016.
本研究调查了创伤后应激障碍（PTSD）症状缓解后，功能损害是否依然存在。对1035名创伤性损伤患者在入院时、3个月（85%）和12个月（73%）时进行了评估。在住院期间及随后的每次评估中，使用世界卫生组织生活质量简表（WHOQOL-BREF）测量创伤性损伤前的生活质量。在3个月和12个月时，使用临床医生施测的PTSD量表评估PTSD。在控制了伤前功能、当前疼痛和共病抑郁后，与从未患PTSD的患者相比，12个月时PTSD症状已缓解的患者在心理（OR = 3.51）、生理（OR = 10.17）、社会（OR = 4.54）和环境（OR = 8.83）领域的生活质量更差。这些数据提供了初步证据，表明即使PTSD症状缓解，其仍可能对功能能力产生持久影响。经Sage许可转载。版权所有© 2016。
