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外源性库欣综合征与非处方补充剂(Artri King)导致的髋部骨折

Exogenous Cushing Syndrome and Hip Fracture Due to Over-the-Counter Supplement (Artri King).

作者信息

Saad-Omer Suhail M, Kinaan Mustafa, Matos Moises, Yau Hanford

机构信息

Department of Internal Medicine, University of Central Florida College of Medicine, University of Central Florida/HCA Florida Healthcare Graduate Medical Education, Orlando, USA.

Department of Internal Medicine, University of Central Florida College of Medicine, Orlando Veterans Affairs Medical Center, Orlando, USA.

出版信息

Cureus. 2023 Jul 2;15(7):e41278. doi: 10.7759/cureus.41278. eCollection 2023 Jul.

Abstract

The most common cause of Cushing syndrome (CS) is exposure to exogenous glucocorticoids. There is an increasing incidence of adulterated over-the-counter (OTC) supplements containing steroids. We present a case of Artri King (AK)-induced CS in a 40-year-old woman who presented with an intertrochanteric fracture of her right femur. Laboratory testing revealed suppressed cortisol and adrenocorticotropic hormone, which was consistent with suppression of the hypothalamic-pituitary-adrenal (HPA) axis. Following the cessation of the AK supplement, the patient's HPA axis recovered, and the clinical manifestations of CS improved. This case emphasizes the need for better regulation of OTC supplements and the need for cautious use.

摘要

库欣综合征(CS)最常见的病因是接触外源性糖皮质激素。含有类固醇的掺假非处方(OTC)补充剂的发病率正在上升。我们报告一例40岁女性因服用“Artri King”(AK)导致的CS,该患者因右股骨粗隆间骨折就诊。实验室检查显示皮质醇和促肾上腺皮质激素受到抑制,这与下丘脑-垂体-肾上腺(HPA)轴受抑制一致。停用AK补充剂后,患者的HPA轴恢复,CS的临床表现有所改善。该病例强调了更好地监管OTC补充剂的必要性以及谨慎使用的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/790f/10315100/f3db2907e925/cureus-0015-00000041278-i01.jpg

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