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[从牙周袋分离出的链球菌的持续性和抗性]

[Persistency and resistance of streptococci isolated from periodontal pockets].

作者信息

Wildfeuer A, Overdiek H F

出版信息

Dtsch Zahnarztl Z. 1979 Apr;34(4):389-91.

PMID:374053
Abstract

Intradermal injection of cell walls or cell wall constituents (Peptidoglycane) of Streptococcus sanguis II in experimental animals caused a similarly severe inflammatory reaction as with Streptococcus A. The three "viridans" species of streptococci proved to be resistant to complement (active serum) as well as to lysozyme and were superior to Streptococcus A in their capacity for resistance to another type of muralytic enzyme isolated from Streptomyces albus. The new acylureido penicillins (Mezlocillin, Azlocillin) had an almost equally inhibitory effect on the growth of the various species of bacteria. The "viridans" and beta-haemolytic types of streptococci which induce a chemotactic reaction in vitro were about equally rapidly and effectively killed in the phagocytes (granulocytes, monocytes) isolated from a patient.

摘要

在实验动物中,皮内注射血链球菌II的细胞壁或细胞壁成分(肽聚糖)会引发与A组链球菌同样严重的炎症反应。事实证明,三种“草绿色”链球菌对补体(活性血清)以及溶菌酶具有抗性,并且在对从白色链霉菌中分离出的另一种溶壁酶的抗性能力方面优于A组链球菌。新型酰脲基青霉素(美洛西林、阿洛西林)对各种细菌的生长几乎具有同等的抑制作用。在体外诱导趋化反应的“草绿色”和β溶血性链球菌在从患者分离出的吞噬细胞(粒细胞、单核细胞)中被杀死的速度和效果大致相同。

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