Department of Ophthalmology and Optometry, Eye and ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, People's Republic of China.
NHC Key Laboratory of Myopia (Fudan University); Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China.
Graefes Arch Clin Exp Ophthalmol. 2024 Jan;262(1):313-321. doi: 10.1007/s00417-023-06133-x. Epub 2023 Jul 5.
To investigate changes in disk halo size after small incision lenticule extraction (SMILE) and the correlation between halo size and lenticule quality in moderate to high myopia.
Thirty eyes of 30 consecutive patients (mean age, 24.9 ± 4.5 years; mean spherical equivalent, -6.85 ± 1.18 D) undergoing SMILE were included in this prospective study. Lenticule surface quality was accessed with a scanning electron microscopy by a scoring system. Halo size was measured preoperatively and at 1, 3, and 6 months postoperatively. Multiple linear regression analysis was performed to explore associations between halo size and a range of factors, including lenticule quality.
Disk halo size increased slightly at 1 month and then recovered continually from 3 to 6 months postoperatively, with no difference between halo size during the preoperative period and at 6 months postoperatively (P > 0.05). One month after SMILE, halo size (1 cd/m, 5 cd/m) was associated only with uncorrected distance visual acuity (P ≤ 0.004). A halo size of 5 cd/m at 3 months postoperatively correlated with the anterior surface quality of the lenticule (P = 0.046). At 6 months postoperatively, a halo size of 1 cd/m was associated only with the baseline, accounting for 11.9% of the variability (P = 0.041); no correlations were found for the halo size of 5 cd/m.
Disk halo size after SMILE was enlarged at an early stage postoperatively and subsequently declined to the baseline level during a 6-month follow-up. The quality of the lenticule surface influenced halo size changes in the early phase.
研究 SMILE 术后盘状光晕大小的变化及中高度近视患者中光晕大小与透镜质量的相关性。
本前瞻性研究纳入了 30 例(30 只眼)连续接受 SMILE 手术的患者(平均年龄 24.9±4.5 岁;平均球镜等效值-6.85±1.18D)。采用扫描电子显微镜评分系统评估透镜表面质量。术前及术后 1、3、6 个月测量光晕大小。采用多元线性回归分析探讨光晕大小与包括透镜质量在内的一系列因素之间的关系。
术后 1 个月光晕大小略有增加,随后从 3 个月持续恢复至 6 个月,术前与术后 6 个月的光晕大小无差异(P>0.05)。SMILE 术后 1 个月,光晕大小(1cd/m,5cd/m)仅与未矫正远视力相关(P≤0.004)。术后 3 个月,5cd/m 的光晕大小与透镜前表面质量相关(P=0.046)。术后 6 个月,1cd/m 的光晕大小仅与基线相关,占可变性的 11.9%(P=0.041);5cd/m 的光晕大小无相关性。
SMILE 术后早期盘状光晕大小增大,随后在 6 个月随访期间降至基线水平。透镜表面质量影响早期光晕大小的变化。