Department of Ophthalmology and Vision Science, The Eye and ENT Hospital of Fudan University, No.19 Baoqing Road, Xuhui District, Shanghai, China.
NHC Key Laboratory of Myopia (Fudan University); Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China.
Graefes Arch Clin Exp Ophthalmol. 2019 Dec;257(12):2789-2793. doi: 10.1007/s00417-019-04481-1. Epub 2019 Oct 29.
To investigate changes in objective disk halo size produced by a glare source after small incision lenticule extraction (SMILE) for myopia correction.
This prospective clinical study included 45 right eyes of 45 patients with a mean age of 25.40 ± 5.06 years and mean spherical equivalent (SE) of - 6.08 ± 1.90 diopters. Disk halo size was measured with a vision monitor before surgery and at postoperative 1 week and 3 months. Other information was collected, including age, SE, lenticule thickness, lenticule diameter, dark pupil, and pupillary response to light parameters (initial diameter; amplitude, latency, duration, and velocity of contraction; latency, duration, and velocity of dilation; and maximum, minimum, and average pupil size).
Compared to preoperative values, disk halo size increased significantly at postoperative 1 week (P = 0.026) and returned to baseline at postoperative 3 months (P = 0.349). Preoperative disk halo size significantly correlated with SE (r = - 0.346, P = 0.020), minimum pupil size (r = 0.365, P = 0.014), and average pupil size (r = 0.310, P = 0.038). Disk halo size at postoperative 1 week was significantly correlated with age (r = 0.324, P = 0.030) and minimum pupil size (r = 0.297, P = 0.047). Disk halo size at postoperative 3 months was significantly correlated with lenticule diameter (r = - 0.362, P = 0.015), initial diameter (r = 0.311, P = 0.037), maximum pupil size (r = 0.312, P = 0.037), minimum pupil size (r = 0.440, P = 0.002), and average pupil size (r = 0.373, P = 0.012).
After SMILE, disk halo size demonstrated a temporary increase and then returned to baseline.
研究近视矫正的小切口透镜切除术(SMILE)后眩光源引起的客观盘晕大小的变化。
本前瞻性临床研究纳入 45 例(45 只眼)年龄 25.40±5.06 岁、平均等效球镜(SE)为-6.08±1.90 屈光度的患者。在术前和术后 1 周及 3 个月使用视力监测仪测量盘晕大小。收集其他信息,包括年龄、SE、透镜厚度、透镜直径、暗瞳孔以及瞳孔对光参数(初始直径;收缩的振幅、潜伏期、持续时间和速度;扩张的潜伏期、持续时间和速度;最大、最小和平均瞳孔大小)的反应。
与术前值相比,术后 1 周时盘晕大小显著增加(P=0.026),术后 3 个月时恢复至基线(P=0.349)。术前盘晕大小与 SE(r=-0.346,P=0.020)、最小瞳孔大小(r=0.365,P=0.014)和平均瞳孔大小(r=0.310,P=0.038)显著相关。术后 1 周盘晕大小与年龄(r=0.324,P=0.030)和最小瞳孔大小(r=0.297,P=0.047)显著相关。术后 3 个月盘晕大小与透镜直径(r=-0.362,P=0.015)、初始直径(r=0.311,P=0.037)、最大瞳孔大小(r=0.312,P=0.037)、最小瞳孔大小(r=0.440,P=0.002)和平均瞳孔大小(r=0.373,P=0.012)显著相关。
SMILE 后,盘晕大小先暂时增加,然后恢复至基线。